Biochemical and Biophysical Parameters Under Thiopental Infusion in Severe Head Injured Patients
The rationale for the use of long term high dose barbiturates depends still on two debated considerations:
a) their efficacy in long term control of intracranial hypertension (IH) refractory to conventional treatment (Rockoff et al. 1979); b) their role in improvement of prognosis through control of ICP (Nordby et al. 1984).
The aim of the study was to evaluate the effects of continuous thiopental (TPS) infusion on intracranial biophysical and biochemical parameters in severe head injured patients.
KeywordsCatheter HPLC Lactate Neurol Diene
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