Redox-Active Iron-Chelators based on Pyridoxal
Electron spin resonance (ESR) and cyclicvoltametric (CV) studies indicate that pyridoxal-based iron chelators of general structure (I) are capable, through metal sequestration (I → II), of transfering single electrons from ferrous ions (II–III) towards the electron-deficient center to yield a free-radical of presumed structure (III). In presence of appropriate electron acceptors [Acc], (III) converts to (IV) with concommitant formation of the corresponding anion radical [Acc]∸. In absence of suitable an electron-acceptor, the intermediacy of a nitrogen-centrered free radical is involved to rationalize the observed generation of double-decomposition products1. Data in substantiation of this view will be presented.
- 1).S. Avramovici-Grisaru and S. Sarel, Chem. Comm. 1986.Google Scholar