Stereoselective C-C Bond Formation in Carbohydrates by Radical Cyclization Reactions.

  • Alain De Mesmaeker
  • Beat Ernst
Conference paper

Abstract

Our strategy for the stereoselective C-C bond formation in carbohydrates is based on intramolecular radical cyclization reactions and offers three major advantages in comparison with the intermolecular processes: a) a more efficient C-C bond formation b) a higher stereoselectivity due to the exclusive formation of a cis ring junction c) only a stoechiometric amount of the radical acceptor (C=C, C≡C) is necessary (in contrast with the large excess normaly used in the intermolecular processes).

Keywords

Hydroxyl Carbohydrate 

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Alain De Mesmaeker
    • 1
  • Beat Ernst
    • 1
  1. 1.Ciba-Geigy Ltd.Central Research LaboratoriesBaselSwitzerland

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