Zusammenfassung
Die intrakavernöse Testung mit vasoaktiven Substanzen wie Papaverin bzw. Papaverin/Phentolamin ist seit der Publikation von Virag 1982 im Lancet [27] zunehmend in den Mittelpunkt des diagnostischen und auch therapeutischen Interesses bei erektiler Dysfunktion (ED) gerückt [1, 2, 4, 5, 7–9, 16–19, 22–24, 26, 28–30]. Bisheriges Hauptproblem in der intrakavernösen Applikation vasoaktiver Substanzen stellte die Induktion interventionsbedürftiger Priapismen von über 6 h Dauer dar, deren Häufigkeit eine deutliche Abhängigkeit von der jeweiligen Patientenselektion zeigt und deshalb in der Literatur zwischen 2% und 15% schwankt [5, 9, 10, 18, 24, 26, 30].
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Abber JC, Lue TF, Orvis BR, McClure RD, Williams RD (1986) Diagnostic tests for impotence: A comparison of papaverine injection with the penile brachial index and nocturnal penile tumescence monitoring. J Urol 135: 923–925
Abozeid M, Juenemann K-P, Luo J-A, Lue TF, Yen T-SB, Tanagho EA (1987) Chronic papaverine treatment: The effect of repeated injections on the Simian erectile response and penile tissue. J Urol 138: 1263–1266
Adaikan PG, Kottegoda SR, Ratnam SS (1986) A possible role for Prostaglandin E1 in human penile erection. Abstract 2. 6, Second World Meeting on Impotence, Prag.
Bähren W, Stief Ch, Scherb W, Gall H, Gallwitz A, Altwein JE (1986) Rationelle Diagnostik der erektilen Dysfunktion unter Anwendung eines pharmakologischen Tests. Aktuel Urol 17: 177–180
Bodner DR, Lindan R, Leffler E, Kursh ED, Resnick MI (1987) The application of intracavernous injection of vasoactive medications for erection in men with spinal cord injury. JUrol 138: 310–311
Bollinger A, Rogatti W (1987) Clinical relevance of Prostaglandin E1. Vasa, Supplement 17
Brindley GS (1983) Cavernosal alpha blockade: A new technique for investigating and treating erectile impotence. Br J Psych 143: 332–335
Buvat J, Lemaire A, Marcolin G, Dehaene JL, Buvat-Herbaut M (1987) Intracavernous injection of papaverine (ICIP). Assessment of its diagnostic and therapeutic value in 100 impotent patients. World J Urol 5: 150–155
Gasser TC, Roach RM, Larsen EH, Madsen PO, Bruskewitz RC (1987) Intracavernous self-injection with phentolamine and papaverine for the treatment of impotence. J Urol 137: 678–680
Halsted DS, Weigel JW, Noble MJ, Mebust WK (1986) Papaverine induced priapism: 2 case reports. J Urol 136: 109–110
Hashmat AI, Abraham J (1987) Papaverine induced priapism, a letal complication. J Urol 137 Number 4, Part 2:201 A
Hedlund A, Andersson K-E (1985) Contraction and relaxation induced by some Prostanoids in isolated human penile erectile tissue and cavernous artery. J Urol 134: 1245–1250
Hue K-N, Burks C, Christy WC (1987) Fibrosis of tunica albuginea: Complication of long-term intracavernous pharmacological self-injection. J Urol 138: 404–405
Ishii N, Watanabe H, Irisawa C, Kikuchi Y (1986) Therapeutic trial with Prostaglandin E1 for organic impotence. Abstract 11. 2, Second World Meeting on Impotence, Prag
Larsen EH, Gasser TC, Bruskewitz RC (1987) Fibrosis of corpus cavernosum after intra-cavernous injection of phentolamine/papaverine. J Urol 137: 292–293
Lue TF, Tanagho EA (1987) Physiology of erection and pharmacological management of impotence. J Urol 137: 829–836
Nellans RE, Ellis LR, Kramer-Levien D (1987) Pharmacological erection: Diagnosis and treatment applications in 69 patients. J Urol 138: 52–54
Padma-Nathan H, Goldstein I, Payton T, Krane RJ (1987) Intracavernosal pharmacotherapy: The pharmacologic erection program. World J Urol 5: 160–165
Porst H, van Ahlen H (1987) Dynamische Cavernosographie und Schwellkörper-Pharmakontestung in der Diagnostik der erektilen Dysfunktion. Urologe A 26: 152–157
Porst H, Tackmann W, van Ahlen H (1987) Bulbokavernosusreflex-Latenzzeitmessung (BCR) und somatosensorisch evozierte Potentiale ( SSEP) in der Diagnostik der erektilen Dysfunktion. Aktuel Urol 18: 198–202
Porst H, van Ahlen H, Vahlensieck W (1987) Relevance of dynamic cavernosography to the diagnosis of venous incompetence in erectile dysfunction. J Urol 137: 1163–1167
Porst H (1987) Erektile Impotenz. Ätiologie, Diagnostik, Therapie. Ferdinand Enke Verlag, Stuttgart
Porst H, van Ahlen H, Köster O, Schlolaut K-H (1988) Vergleich von Papaverininduzierter Doppler-Sonographie und Angiographie in der Diagnostik der erektilen Dysfunktion. Urologe A, 27: 8–13
Sidi AA, Chen K-K (1987) Clinical experience with vasoactive intracavernous pharmaco-therapy for treatment of impotence. World J Urol 5: 156–159
Stackl W, Loupal G, Holzmann A (1986) Intracavernous injection of vasoactive drugs in the rabbit. Abstract 11. 16, Second World Meeting on Impotence, Prag
Stief CG, Bähren W, Gall H, Scherb W, Gallwitz A, Altwein JE (1986) Schwellkörper-Autoinjektionstherapie (SKAT): Erste Erfahrungen bei erektiler Dysfunktion. Urologe A 25: 63–66
Virag R (1982) Intracavernous injection of papaverine for erectile failure. Lancet 11: 938
Virag R, Sussman H, Floresco J, Shoukry K (1987) Late results on the treatment of neurogenic impotence by self-intracavernous-injection ( SICI) of vasoactive drugs. World J Urol 5: 166–170
Virag R, Adaikan PG (1987) Effects of Prostaglandin E1 on penile erection and erectile failure. Letters to the editor. J Urol 137: 1010
Zorgniotti AW, Lefleur RS (1985) Auto-injection of the corpus cavernosum with a vasoactive drug combination for vasculogenic impotence. J Urol 133: 39–41
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Porst, H., Rogatti, W. (1988). Stellenwert von Prostaglandin E1 (PGE1) in der Diagnostik und Therapie der erektilen Dysfunktion. In: Heidrich, H., Böhme, H., Rogatti, W. (eds) Prostaglandin E1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73943-9_21
Download citation
DOI: https://doi.org/10.1007/978-3-642-73943-9_21
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73944-6
Online ISBN: 978-3-642-73943-9
eBook Packages: Springer Book Archive