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Connectors of Supramolecular Assemblies

  • J. H. Fessler
  • B. Blumberg
  • A. G. Campbell
  • K. Garrison
  • A. J. MacKrell
  • R. E. Nelson
  • P. F. Olson
  • L. I. Fessler
Conference paper
Part of the Springer Series in Biophysics book series (BIOPHYSICS, volume 3)

Abstract

An underlying theme of this meeting is the search for potential biophysical relationships between the extracellular matrix and the cytoskeleton. We found that the fruit fly, Drosophila melanoqaster. shares with vertebrates some major extra-cellular matrix components that are adjacent to cell surfaces, and also a transmembrane receptor of the integrin type. Actin filaments are probably indirectly linked to the cytoplasmic portion of such receptors in vertebrates and very similar actins exist in Drosophila. This suggests that parts of the molecular relationships between the extracellular matrix and the cytoplasm have been conserved during evolution, and that these mechanisms are likely to have important roles in cell biology.

Keywords

Basement Membrane Supramolecular Assembly Basement Membrane Component Actual Amino Acid Basement Membrane Collagen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. H. Fessler
    • 1
  • B. Blumberg
    • 1
  • A. G. Campbell
    • 1
  • K. Garrison
    • 1
  • A. J. MacKrell
    • 1
  • R. E. Nelson
    • 1
  • P. F. Olson
    • 1
  • L. I. Fessler
    • 1
  1. 1.Molecular Biology Institute and the Department of BiologyUniversity of California, Los AngelesLos AngelesUSA

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