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Structure and Spatial Organisation of Intermediate Filament and Nuclear Lamin Molecules

  • Conference paper
Cytoskeletal and Extracellular Proteins

Part of the book series: Springer Series in Biophysics ((BIOPHYSICS,volume 3))

Abstract

Intermediate filament structure has been investigated extensively and much is now known about the conformation of IF chains, their aggregation into two-stranded molecules, the modes of assembly of the molecules into four-chain structural units and the arrangement of units in the IF (Geisler and Weber, 1982; Hanukoglu and Fuchs, 1982; Crewther et al, 1983; Steinert et al, 1983,1984; Parry and Fraser, 1985; Steinert and Parry 1985, Parry et al, 1986; McKeon et al, 1986). This knowledge provides the basis for further experimentation and analysis and allows new insights to be presented here on the role of the conserved sequences in the rod domain, the antiparallel arrangement of IB segments and the flexibilities of the terminal domains.

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Authors and Affiliations

  1. Department of Physics and Biophysics, Massey University, Palmerston North, New Zealand

    James F Conway & David A D Parry

Authors
  1. James F Conway
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  2. David A D Parry
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Editors and Affiliations

  1. Maurice E. Müller-Institut, Biozentrum der Universität Basel, Klingelbergstraße 70, CH-4056, Basel, Germany

    Ueli Aebi

  2. Abteilung für Biophysikalische Chemie, Biozentrum der Universität Basel, Klingelbergstraße 70, CH-4056, Basel, Germany

    Jürgen Engel

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© 1989 Springer-Verlag Berlin Heidelberg

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Conway, J.F., Parry, D.A.D. (1989). Structure and Spatial Organisation of Intermediate Filament and Nuclear Lamin Molecules. In: Aebi, U., Engel, J. (eds) Cytoskeletal and Extracellular Proteins. Springer Series in Biophysics, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73925-5_28

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  • DOI: https://doi.org/10.1007/978-3-642-73925-5_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73927-9

  • Online ISBN: 978-3-642-73925-5

  • eBook Packages: Springer Book Archive

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