Functional Analysis of Actin Binding Proteins In Vitro and In Vivo
A large number of actin-binding proteins has been isolated from different organisms. Similar interactions with G- or F-actin indicate that they represent classes of proteins with conserved functions during evolution. Data emerging from comparisons of protein- and DNA-sequences support this notion. We have started a search for novel actin-binding proteins in Dictvostelium discoideum which may reveal new classes of generally important proteins.