Molecular Properties of Dihydropyridine-Sensitive Calcium Channels from Skeletal Muscle

  • M. J. Seagar
  • M. Takahashi
  • W. A. Catterall
Conference paper
Part of the Bayer AG Centenary Symposium book series (BAYER)


Voltage-sensitive calcium channels provide an essential link between transient changes in membrane potential and a variety of cellular responses. In neurons, calcium influx couples membrane depolarization to transmitter release at the synaptic terminal [1], whereas in the cell body it may activate calcium-dependent potassium channels and thus modulate repetitive firing patterns [2]. In cardiac and smooth muscle tissue, calcium channels mediate excitation-contraction coupling, although in skeletal muscle their physiological role is still a matter for debate [3,4].


Calcium Channel Wheat Germ Agglutinin Dihydropyridine Calcium Antagonist Nitrocellulose Strip Calcium Channel Subunit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • M. J. Seagar
    • 1
  • M. Takahashi
    • 1
  • W. A. Catterall
    • 1
  1. 1.Department of PharmacologyUniversity of WashingtonSeattleUSA

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