The Voltage Sensor of Skeletal Muscle Excitation-Contraction Coupling: A Comparison with Ca2+ Channels

  • G. Pizarro
  • G. Brum
  • M. Fill
  • R. Fitts
  • M. Rodriguez
  • I. Uribe
  • E. Rios
Conference paper
Part of the Bayer AG Centenary Symposium book series (BAYER)

Abstract

A recent development in the study of Ca2+ channels is the realization [2, 44] that skeletal muscle Ca2+ channels have a number of properties in common with the voltage sensor of excitation-contraction (Ee) coupling, the molecule or structure of skeletal muscle membrane that has the role of sensing the action potential to control the opening of the Ca2+ release channels of the sarcoplasmic reticulum (SR).

Keywords

Triad Verapamil Nifedipine Cesium EGTA 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • G. Pizarro
    • 1
  • G. Brum
    • 1
  • M. Fill
    • 1
  • R. Fitts
    • 1
  • M. Rodriguez
    • 1
  • I. Uribe
    • 1
  • E. Rios
    • 1
  1. 1.Department of PhysiologyRush UniversityChicagoUSA

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