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Drugs for the Treatment of Parkinson’s Disease pp 149–163Cite as

Receptors in the Basal Ganglia

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 88))

Abstract

The study of both presynaptic and postsynaptic markers of neurotransmitter systems in the basal ganglia has afforded a great deal of information about the function of specific neuronal pathways in health and disease. In Parkinson’s disease, the emphasis has been on the study of dopamine presynaptic and postsynaptic elements. Other neurotransmitter abnormalities, however, have been observed in this and other basal ganglia diseases. This chapter will focus on the normal distribution of neurotransmitter receptors in human basal ganglia and the receptor abnormalities observed in Parkinson’s disease.

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Authors
  1. A. B. Young
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  2. J. B. Penney
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Editors and Affiliations

  1. Division of Neurology, UBC Health Sciences Centre Hospital, 2211 Wesbrook Mall, Vancouver, British Columbia, Canada, V6T 1W5

    Donald B. Calne Professor D.M., F.R.C.P., F.R.C.P.C. (Head) (Head)

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© 1989 Springer-Verlag Berlin Heidelberg

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Young, A.B., Penney, J.B. (1989). Receptors in the Basal Ganglia. In: Calne, D.B. (eds) Drugs for the Treatment of Parkinson’s Disease. Handbook of Experimental Pharmacology, vol 88. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73899-9_4

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  • DOI: https://doi.org/10.1007/978-3-642-73899-9_4

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  • Print ISBN: 978-3-642-73901-9

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