Abstract
An important problem in the treatment of Parkinson’s disease (PD) is the large number of patients who, after a good response to levodopa, fail to maintain this response and become more symptomatic. Increasing disability is usually accompanied by dyskinesias and diurnal fluctuations in performance, predominantly “wearing-off” phenomena (Marsden and Parkes 1977; 1976). Occasionally, patients exhibit abrupt random fluctuations: “on-off” phenomena.
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© 1989 Springer-Verlag Berlin Heidelberg
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Lieberman, A.N., Goldstein, M. (1989). Update on Bromocriptine in Parkinson’s Disease. In: Calne, D.B. (eds) Drugs for the Treatment of Parkinson’s Disease. Handbook of Experimental Pharmacology, vol 88. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73899-9_17
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DOI: https://doi.org/10.1007/978-3-642-73899-9_17
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