Return of Function After Optic Tract Lesions in Adult Rats: Spontaneous Axonal Regeneration?
It is unusual to see a spontaneous regeneration of severed axons suggested as one of the many possible mechanisms which may contribute to the often-observed improvement in functions which were compromised immediately after injury to the adult mammalian central nervous system (CNS). Severed axons in the CNS do not generally show the vigorous, albeit often randomly directed, regrowth of peripheral axons (Ramón y Cajal 1928), and it is rare to find that they have crossed a cut unless induced to do so by adjacent implanted tissue which they enter, but within which they tend to remain (Kromer et al. 1981; So and Aguayo 1985; Berry et al. 1986; Vidal-Sanz et al. 1987).
KeywordsRetinal Ganglion Cell Superior Colliculus Retinal Projection Partial Lesion Support Wire
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