Optokinetic and Vestibular Oculomotor Responses and their Interaction Following Hemilabyrinthectomy in the Cat
One of the most striking examples of plasticity in the central nervous system is the compensation of the highly disabling deficits which result from unilateral peripheral vestibular lesions. In fact, many studies in different species (cf. Schaefer and Meyer 1974) have shown that the vestibular compensation processes are remarkable both in their speed and in the degree of functional recovery. In particular, ocular and postural imbalance subside almost completely within the first post-operative week, and behavioral tests in cats and monkeys have shown that 30–40 days after hemilabyrinthectomy (HL) the recovery of postural and locomotor abnormalities is so extensive that it is often difficult to distinguish between operated and non-operated animals (Lacour et al. 1976; Xerri and Lacour 1980).
KeywordsDepression Retina Amphetamine
Unable to display preview. Download preview PDF.
- Cheron G, Gillis P, Godaux E (1986) Lesions in the cat prepositus complex: effects on the op-tokinetic system. J Physiol (Lond) 372: 95–111Google Scholar
- Cohen B, Uemura T, Takemori S (1973) Effects of labyrinthectomy on optokinetic nystagmus and optokinetic afternystagmus. Equilibrium Res 3: 88–93Google Scholar
- Maioli C, Precht W, Ried S (1982) Vestibuloocular and optokinetic reflex compensation following hemilabyrinthectomy in the cat. In: Roucoux A, Crommelinck M (eds) Physiological and pathological aspects of eye movements. Junk, The Hague, pp 202–208Google Scholar
- Precht W, Maioli C, Dieringer N, Cochran S (1981) Mechanisms of compensation of the vestibulo-ocular reflex after vestibular neurotomy. In: Flohr H, Precht W (eds) Lesion-induced neuronal plasticity in sensorimotor systems. Springer, Berlin Heidelberg New York, pp 221–230Google Scholar
- Schaefer KP, Meyer DL (1974) Compensation of vestibular lesions. In: Kornhuber HH (ed) Handbook of sensory physiology, vol VI/2. Springer, Berlin Heidelberg New York, pp 463–490Google Scholar
- Uemura T, Cohen B (1973) Effects of vestibular nuclei lesions on vestibulo-ocular reflexes and posture in monkeys. Acta Oto-Laryngol 315: 1–71Google Scholar
- Wolfe JW, Kos CM (1977) Nystagmic responses of the rhesus monkey to rotational stimulation following unilateral labyrinthectomy: final report. Trans Am Acad Ophthalmol Oto-Laryngol 84: 38–45Google Scholar