Structural Studies on Crystals of Ribosomal Particles

  • A. Yonath
  • H. G. Wittmann

Abstract

Ribosomes, the universal cell organelles on which protein biosynthesis takes place, consist of two subunits which associate upon initiation of the biosynthetic process. Each ribosomal subunit is a defined assembly of proteins and ribonucleic acid chains. A typical bacterial ribosome, e.g. that of Escherichia coli, has a molecular weight of 2.300.000 Dalton. Its large (50S) subunit is of 1.450.000 Dalton and consists of 33 different proteins and 2 RNA chains. The small subunit (30S) is of 850.000 Dalton and contains 21 proteins and 1 RNA chain (Wittmann, 1982).

Keywords

Ribosomal Subunit Protein Biosynthesis Bacillus Stearothermophilus Large Ribosomal Subunit tRNA Molecule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • A. Yonath
    • 1
    • 2
  • H. G. Wittmann
    • 3
  1. 1.Dept. Structural ChemistryWeizmann InstituteRehovotIsrael
  2. 2.Max-Planck-Research-Unit for Structural Molecular BiologyHamburg 52Germany
  3. 3.Max-Planck-Institut für Molekulare GenetikGermany

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