Advertisement

Hair and Nail

  • R. P. R. Dawber
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 87 / 1)

Abstract

Since hair and nail are derived embryologically from the same tissue — the primitive epidermis — it is logical to consider them together. The definitive hair follicle complement and the nail apparatus are both fully developed by 20 weeks in utero. It is of interest that in many congenital and acquired ectodermal and integumentary diseases hair and nail changes are commonly seen though in acquired diseases predominantly affecting the epidermis, nail changes are frequently present whereas the hair follicle may remain normal. This may in part reflect greater evolutionary and embryological development away from the epidermis:as will be discussed later, the epidermis and nail apparatus grow continuously throughout life whilst hair is produced intermittently in the hair cycle.

Keywords

Hair Follicle Dermal Papilla Hair Shaft Nail Plate Outer Root Sheath 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Achten G (1968) Normale Histologic und Histochemie des Nagels. In:Jadassohn J (ed) Handbuch der Haut- und Geschlechtskrankheiten. Springer, Berlin Heidelberg New York, pp 339–376Google Scholar
  2. Baran R, Dawber RPR (1984) Diseases of the nails and their management, 1st edn. Blackwell, Oxford Burrows MT (1919) The significance of the lunula of the nail. Johns Hopkins Hosp Rep 18:357–361Google Scholar
  3. Ebling FJ (1981) Hormonal control of hair growth. In:Orfanos CE, Montagna W, Stuttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 195–204Google Scholar
  4. Epstein W, Maibach HI (1969) Cell proliferation and movement in human hair bulbs. In:Montagna W, Dobson RL (eds) Advances in biology of skin. Pergamon, New YorkGoogle Scholar
  5. Forslind B, Wroblewski R, Alzelius BA (1976) Calcium and sulphur location in human nail. J Invest Dermatol 67:223CrossRefGoogle Scholar
  6. Hamilton JB (1951) Patterned long hair in man; types and incidence. Ann NY Acad Sci 53:708PubMedCrossRefGoogle Scholar
  7. Jarrett A, Spearman RI (1966) The histochemistry of the human nail. Arch Dermatol 94:652PubMedCrossRefGoogle Scholar
  8. Johnson E (1977) The control of hair growth. In: Jarrett A (ed) Physiology and pathophysiology of the skin, vol 4. The hair follicle. Academic, London, p 1351Google Scholar
  9. Leshin M, Wilson JD (1981) Mechanisms of androgen-mediated hair growth. In:Orfanos CE, Montagna W, Stuttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 205–209Google Scholar
  10. Lewin K (1965) The normal fingernail. Br J Dermatol 77:421PubMedCrossRefGoogle Scholar
  11. Lewis BL, Montgomery H (1955) The senile nail. J Invest Dermatol 24:11–18PubMedGoogle Scholar
  12. Ludwig E (1977) Classification of the types of androgenic alopecia arising in the female sex. Br J Dermatol 97:249CrossRefGoogle Scholar
  13. Oliver RF (1970) The induction of follicle formation in the hooded rat by vibrissae dermal papillae. J Embryol Exp Morphol 23:219PubMedGoogle Scholar
  14. Parent D, Achten G, Stouffs-Vanhoof F (1985) Ultrastructure of the normal human nail. Am J Dermato-pathol 1 (6):529–535CrossRefGoogle Scholar
  15. Pinkus F (1927) In:Jadassohn J (ed) Handbuch der Haut- und Geschlechtskrankheiten. Springer, Berlin, pp 267–289Google Scholar
  16. Rook RA, Dawber RPR (1982) Diseases of the hair and scalp. Blackwell Scientific, Oxford, pp 10–14Google Scholar
  17. Ryan TJ (1973) The arterio-venous anastomoses. In:Jarrett A (ed) The physiology and pathophysiology of the skin, vol 2. Academic, London, p 612Google Scholar
  18. Saitoh M, Uzuka M, Sakamoto M (1970) Human hair cycle. J Invest Dermatol 54:65PubMedCrossRefGoogle Scholar
  19. Straille WE (1965) Root sheath — dermal papillary relationships in the control of hair growth. In:Lyne AC, Shorth BF (eds) Biology of skin and hair growth. Angus and Robertson, Sydney, pp 35–37Google Scholar
  20. Stroud JD (1980) Complementation of the inner root sheath of human hair. In:Brown AC, Crounse RG (eds) Hair, trace elements and human illness. Praeger, New York, pp 163–168Google Scholar
  21. Swift JA (1977) The histology of keratin fibres. In:Asquith RS (ed) The chemistry of natural protein fibres. Wiley, London, pp 81–146CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • R. P. R. Dawber

There are no affiliations available

Personalised recommendations