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Structure, Function and Control: Afferent Nerve Endings in the Skin

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Pharmacology of the Skin I

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 87 / 1))

Abstract

The skin is an important sensory structure concerned with the physical nature of our immediate environment (e.g. its temperature or roughness) and its own internal state (e.g. the degree of stretch or the presence of inflammatory chemical agents). In Sects. C—E the structure and function of the specialised nerve endings concerned with innocuous mechanical stimuli (Sect. C), with innocuous temperature changes (Sect. D) and with noxious, potentially or actually damaging, stimuli (Sect. E) will be considered in turn. Most of our knowledge of the function of cutaneous nerve endings has been deduced from recordings from afferent nerve fibres some distance from the receptor endings themselves. The fibre composition of cutaneous nerves will thus be considered first in Sect. B. Finally, Sect. G will consider what is currently known about the responses of cutaneous receptors to drugs.

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Authors
  1. B. Lynn
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Editors and Affiliations

  1. The Institute of Dermatology, St. Thomas’s Hospital, Lambeth Palace Road, SE1 7EH, London, Great Britain

    Malcolm W. Greaves M.D., Ph.D., F.R.C.P.

  2. Department of Dermatology, The Royal Victoria Infirmary, The University of Newcastle upon Tyne, NE1 4LP, Newcastle upon Tyne, Great Britain

    Sam Shuster M.D., F.R.C.P.

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Lynn, B. (1989). Structure, Function and Control: Afferent Nerve Endings in the Skin. In: Greaves, M.W., Shuster, S. (eds) Pharmacology of the Skin I. Handbook of Experimental Pharmacology, vol 87 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73797-8_10

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  • DOI: https://doi.org/10.1007/978-3-642-73797-8_10

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