Abstract
Synthetic steroid hormones are generally accepted as a safe and efficacious means of fertility control. However, the formulations currently available fall short of ideal with regard to ease of administration and lack of side effects. There are questions regarding safety following long-term use of formulations containing estrogen, and efficacy may be compromised due to failure of user compliance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Beck LR, Pope VZ (1984) Controlled-release delivery system for hormones; a review of their properties and current therapeutic use. Drugs 27:528
Beck LR, Tice TR (1983) Poly (lactic acid) and poly (lactic acid-co-glycolic acid) contraceptive delivery system. In: Mishell DR Jr (ed) Long-acting steroid contraception, vol 2. Raven, New York, pp 175–199
Beck LR, Cowsar DR, Lewis DH, Cosgrove RJ Jr, Riddle CT, Lowry SL, Epperly T (1979) A new long-acting injectable microcapsule system for the administration of progesterone. Fertil Steril 31:545
Beck LR, Cowsar DR, Lewis DH, Gibson JW, Flowers CE Jr (1979) New long-acting injectable microcapsule contraceptive system. Am J Obstet Gynecol 135:419
Beck LR, Cowsar DR, Pope VZ (1980) Long-acting steroidal contraceptive systems. In: Zatuchni GI (ed) Research frontiers in fertility regulation, vol 1./1. PARFR/North- western University, Chicago
Beck LR, Ramos RA, Flowers CE Jr, Lopez GZ, Lewis DH, Cowsar DR (1981) Clinical evaluation of injectable biodegradable contraceptive system. Am J Obstet Gynecol 140:799
Beck LR, Flowers CE Jr, Pope VZ, Tice TR, Dunn RL, Gilley RM (1983) Poly (d, 1- lactide-co-glycolide)/norethisterone microcapsules: clinical study. In: Zatuchni GI, Goldsmith A, Shelton JD, Sciarra JJ (eds) Long-acting contraceptive delivery systems. Harper and Row, Philadelphia, pp 407–417
Beck LR, Flowers CE Jr, Pope VZ, Tice TR (1983) Clinical evaluation of an improved injectable microcapsule contraceptive system. Am J Obstet Gynecol 147:815
Beck LR, Pope VZ, Flowers CE jr, Cowsar DR, Tice TR, Lewis DH, Dunn RL, Moore AB, Gilley RM (1983) Poly (d, 1-lactide-co-glycolide) norethisterone microcapsules; an injectable biodegradable contraceptive. Biol Reprod 28:186
Goldzieher JW, Benagiano G (1982) Long-acting injectable steroid contraceptives. In: Mishell DR Jr (ed) Advances in fertility research, vol 1. Raven, New York, pp 75–115
Lewis DH, Tice TR (1983) Polymeric consideration in the design of microencapsulation of contraceptive steroids. In: Zatuchni GI, Goldsmith A, Shelton JD, Sciarra JJ (eds) Long-acting contraceptive system. Harper and Row, Philadelphia, pp 77–95
Mishell DR (ed) (1983) Long-acting steroid contraception. Raven, New York
Rivera R, Flores C, Aldaba S, Hernandez A (1984) Norethisterone microspheres 6- month system: clinical results. In: Zatuchni GI, Goldsmith A, Shelton JD, Sciarra JJ (eds) Long-acting contraceptive delivery systems. Harper and Row, Philadelphia, pp 418–424
Zatuchni GI, Goldsmith A, Shelton JD, Sciarra J J (eds) (1984) Long-acting contraceptive systems. Harper and Row, Philadelphia
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Zatuchni, G.I., Beck, L.R., Lewis, D.H. (1988). Long-Acting Injectable Steroidal Contraception Utilizing Norethindrone Microspheres. In: Runnebaum, B., Rabe, T., Kiesel, L. (eds) Female Contraception. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73790-9_19
Download citation
DOI: https://doi.org/10.1007/978-3-642-73790-9_19
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73792-3
Online ISBN: 978-3-642-73790-9
eBook Packages: Springer Book Archive