Neurotoxicology of heavy metals: Synaptic transmission as influenced by mono- and divalent metalcations

  • H. Wiegand
Conference paper


Divalent, essential cations like magnesium-, zink- or calciumions play a pivotal role in many biological processes and are effective in relatively low concentrations. In many organs the action of heavy metals is manifested by an interaction with the physiological functions especially of calcium, i.e. in the nervous system the regulation of transmitter-release in synaptic transmission.


Synaptic Transmission Neuromuscular Junction Presynaptic Nerve Terminal Endplate Potential Presynaptic Nerve Ending 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • H. Wiegand
    • 1
  1. 1.Medical Institute of Environmental Hygiene at the University of DüsseldorfDüsseldorfGermany

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