Abstract
Ozone and nitrogen dioxide are major toxic components of photochemical smog. The morphological, physiological and biochemical effects on the respiratory system of man and experimental animals have been investigated over the last decades.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alink, G.M., J.C.M. van der Hoeven, F.M.H. Debets, W.S.M. van de Ven, J.S.M. Boley and J.H. Koeman (1979) A new exposure model for in vitro testing of effects of gaseous pollutants on mammalian cells by means of gas diffusion through plastic films, Chemosphere, 2, 63–73.
Evans, M.J., L.V. Johnson, R.J. Stephans and G. Freeman (1976) Renewal of the terminal bronchiolar epithelium in the rat following exposure to N02 or 03, Lab. Invest., 35, 246–257.
Mason, R.J., M.C. Williams, R.C. Greenleaf and J.A. Clements (1977) Isolation and properties of type II alveolar cells from rat lung, Am. Rev. Resp. Dis., 115, 1015–1026.
Rietjens, I.M.C.M., G.M. Alink and R.M.E. Vos (1985) The role of glutathione and changes in thiol homeostasis in cultured lung cells exposed to ozone, Toxicology, 35, 207–217.
Rietjens, I.M.C.M., M.C.M. Poelen, R.A. Hempenius, M.J.J. Gijbels and G.M. Alink (1986) Toxicity of ozone and nitrogen dioxide to alveolar macrophages: comparative study revealing differences in their mechanism of toxic action, J. Toxicol. Environ. Health, 19, 555–568.
Rietjens, I.M.C.M., H.H. Lemmink, G.M. Alink and P.J. van Bladeren (1987) The role of glutathione and glutathione S-transferases in fatty acid ozonide detoxification, Chem.-Biol. Interactions, 62, 3–14.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Alink, G.M., Rietjens, I.M.C.M. (1988). Mechanisms of O3 and NO2 Toxicity in Lung Cells in Vitro. In: Seemayer, N.H., Hadnagy, W. (eds) Environmental Hygiene. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73766-4_2
Download citation
DOI: https://doi.org/10.1007/978-3-642-73766-4_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73768-8
Online ISBN: 978-3-642-73766-4
eBook Packages: Springer Book Archive