Menispermum dauricum DC.

  • Weici Tang
  • Gerhard Eisenbrand


Beiduogen, Rhizoma Menispermi, is the dry rootstock of Menispermum dauricum DC. (Menispermaceae), which occurs widely in China. It is a traditional Chinese medicine and is now officially listed in the Chinese Pharmacopoeia. Beiduogen Pian, Tabellae Menispermi, is another official item produced from the total alkaloidal extract of M. dauricum. The rhizome as well as the tablets are used as an analgesic and antipyretic.


Calcium Gluconate Isoquinoline Alkaloid Acta Acad Respiratory Paralysis Related Alkaloid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Tomita M, Okamoto Y (1964) Alkaloids of menispermaceous plants. CCVIII. Alkaloids of Menispermum dauricum. Yakugaku Zasshi [Suppl 3] 84:1030–1031PubMedGoogle Scholar
  2. 2.
    Sun YQ, Gao CY, Zhang LX, Zhang AJ, Li FM, Wang LQ, Cai H (1984) Study of chromatography and spectrometry for Chinese medicines. II. TLC analysis and HPLC separation for the total alkaloid and injections of the root of Menispermum dauricum DC. J Shenyang Coll Pharm 1:223–227Google Scholar
  3. 3.
    Tomita M, Okamoto Y, Nagai Y, Tanaka S, Hayata T (1970) Alkaloids of menispermaceous plants. CCLVIIL Alkaloids of Menispermum dauricum. Basic components of Siberian Menispermum dauricum. Yakugaku Zasshi 90:1182–1186PubMedGoogle Scholar
  4. 4.
    Tomita M, Okamoto Y, Nagai Y, Kitayama K, Yanagawa H (1970) Alkaloids of menispermaceous plants. CCLVII. Alkaloids of Menispermum dauricum. Structure of a new tertiary phenolic biseoclaurine type alkaloid dauricoline. Yakugaku Zasshi 90:1178–1181PubMedGoogle Scholar
  5. 5.
    Tomita M, Okamoto Y (1965) Alkaloids of menispermaceous plants. CCIX. Alkaloids of Menispermum dauricum. 4. The structure of a new tertiary biseoclaurine type alkaloid “daurinoline”. Yakugaku Zasshi 85:456–459PubMedGoogle Scholar
  6. 6.
    Zheng XW, Min ZD, Zhao SX (1979) A new alkaloid of Menispermum dauricum, daurisoline. Kexue Tongbao 24:285–288Google Scholar
  7. 7.
    Tomita M, Kikuchi T (1955) Alkaloids of menispermaceous plants. CXXIV. Alkaloids of Menispermum dauricum. Pharm Bull Jpn 3:100–104Google Scholar
  8. 8.
    Ilinskaya TN (1956) Alkaloids of Menispermum dauricum. Dokl Akad Nauk SSSR 108:1081–1082Google Scholar
  9. 9.
    Okamoto Y, Tanaka S, Kitayama K, Isomoto M, Masaishi M, Yanagawa H, Kunimoto J (1971) Alkaloids of menispermaceous plants. CCLXI. Alkaloids of Menispermum dauricum. 8. Yakugaku Zasshi 91:684–687PubMedGoogle Scholar
  10. 10.
    Hou CY, Xue H (1985) Studies on chemical constituents of Menispermum dauricum DC. Acta Pharm Sin 20:112–117Google Scholar
  11. 11.
    Hou CY, Xue H (1984) Studies on the chemical constituents of Menispermum dauricum DC. Acta Pharm Sin 19:471–472Google Scholar
  12. 12.
    Takani M, Takasu Y, Takahashi K (1983) Studies on constituents of medicinal plants. XXIII. Constituents of the vines of Menispermum dauricum DC. 2. Chem Pharm Bull (Tokyo) 31:3091–3093Google Scholar
  13. 13.
    Kumitomo J, Satoh M, Shingu T (1983) Studies on the alkaloids of menispermaceous plants. CCLXXIX. Alkaloids of Menispermum dauricum DC. 9. Structure and synthesis of menisporphine, a new type of isoquinoline alkaloid. Tetrahedron 39:3261–3265CrossRefGoogle Scholar
  14. 14.
    Tomita M, Okamoto Y, Kikuchi T, Osaki K, Nishikawa M, Kamiya K, Sasaki Y, Matoba K, Goto K (1971) Alkaloids of menispermaceous plants. CCLIX. Alkaloids of Menispermum dauricum. Structure of acutumine and acutumidine, chlorine-containing alkaloids with a novel skeleton. Chem Pharm Bull (Tokyo) 19:770–791Google Scholar
  15. 15.
    Chen SH, Hu CJ (1982) Effect of dauricine on aortic stripe. Acta Pharmacol Sin 3:178–182Google Scholar
  16. 16.
    Li GR, Fang DC, Hu CJ, Lu FH (1984) Effects of dauricine on physiologic properties of cat myocardium papillary muscle. Acta Pharmacol Sin 5:20–22Google Scholar
  17. 17.
    Li GR, Fang DC, Hu CJ, Lu FH (1983) Effects of dauricine on the concentration-response curve of isoprenaline and calcium and the electromechanical activity of the cat papillary muscle. Acta Pharm Sin 18:660–664Google Scholar
  18. 18.
    Li GR, Hu CJ, Lu FH (1983) Effects of dauricine on ECG and its local anesthetic activity. Acta Acad Med Wuhan 12:280–282Google Scholar
  19. 19.
    Chen SH, Wu CJ (1981) Antihypertensive action of dauricine. Chin Trad Herb Drugs 12:450Google Scholar
  20. 20.
    Chen SH, Hu CJ (1982) Hypotensive effect of dauricine and preliminary elucidation of its mechanism. Acta Acad Med Wuhan 11:75–78Google Scholar
  21. 21.
    Zeng FD, Zeng WC, Leng DM, Hu CJ (1984) Effects of dauricine and verapamil on systolic time intervals and blood pressure in anesthetized cats. Acta Acad Med Wuhan 13:205–208Google Scholar
  22. 22.
    Dai ZS, Hou SX, Guo LY, Hu CJ (1983) Absorption, distribution and excretion of dauricine in rats. Chin Pharm Bull 18:278–279Google Scholar
  23. 23.
    Dai ZS, Yi MG, Li J, Hu CJ (1983) Study on the pharmacokinetics of 3H-dauricine. Acta Acad Med Wuhan 12:290–291Google Scholar
  24. 24.
    Hou SX, Dai ZS, Wang FJ, Guo LJ, Hu CJ (1982) Pharmacokinetic studies on dauricine. Acta Pharm Sin 17:863–865Google Scholar
  25. 25.
    Gong T, Wu ZY (1979) Pharmacological effects of daurisoline methyl bromide, a preliminary report. Acta Pharm Sin 14:439–442Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Weici Tang
    • 1
  • Gerhard Eisenbrand
    • 1
  1. 1.Lebensmittelchemie und UmwelttoxikologieUniversität KaiserslauternKaiserslauternGermany

Personalised recommendations