Fraxinus spp.

  • Weici Tang
  • Gerhard Eisenbrand


Qinpi, Cortex Fraxini, is the dry barks from stem or branches of the following Fraxinus species: F. rhynchophylla Hance, F. chinensis Roxb., F. chinensis Roxb. var. acuminata Lingelsh., or F. stylosa Lingelsh. (Oleaceae) collected in spring and the fall. It is officially listed in the Chinese Pharmacopoeia and is used in traditional Chinese medicine as an astringent for the treatment of diarrhea and as an antiphlogistic in ophthalmology for the treatment of conjunctivitis.


Chinese Drug Chinese Pharmacopoeia Mast Tumor Cell Aesculus Hippocastanum Platelet Cyclooxygenase 
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  1. 1.
    Mei PF, Hsu CC, Wang Y (1962) Active principles of the Chinese drug Chin Pie (Fraxinus rhychophylld). Acta Chim Sin 28:25–30Google Scholar
  2. 2.
    Head FSH, Robertson A (1930) Natural glucosides, part II. The constitution of aesculin. J Chem Soc 2434–2444Google Scholar
  3. 3.
    Tiemann F, Will W (1882) Zur Konstitution des Aesculetins. Chem Ber 15:2072–2083CrossRefGoogle Scholar
  4. 4.
    Will W, Albrecht K (1884) Über einige Pyrogallussäure- und Phloroglucinderivate und die Beziehungen derselben zu Daphnetin und Aesculetin. Chem Ber 17:2098–2109CrossRefGoogle Scholar
  5. 5.
    Ueno K, Saito N (1977) Esculetin; 6,7-dihydroxycoumarin. Acta Crystallogr [B] B33:283–285CrossRefGoogle Scholar
  6. 6.
    Zhang XQ, Xu LX (1982) Polarographic determination of aesculetin iñ Qin Pi (Fraxinus rhychophylla Hance or F. chinensis Roxb.). Acta Pharm Sin 17:305–308Google Scholar
  7. 7.
    Zeng MY, Fu GL, Wu JL (1982) Assay of aesculin and aesculetin in Qin Pi. Bull Chin Mat Med 7:26–29Google Scholar
  8. 8.
    Guo XS, Zhang YZ (1983) HPLC separation and determination of active principles in Chin Pie (Fraxinus chinensis). Acta Pharm Sin 18:525–528Google Scholar
  9. 9.
    Wessely F, Demmer E (1929) Konstitution und Eigenschaften des Fraxins. Chem Ber 62:120Google Scholar
  10. 10.
    Guo XS, Zhang YZ (1983) Chemical studies on the Chinese drug Qin Pi, the bark oí Fraxinus stylosa. Acta Pharm Sin 18:434–439Google Scholar
  11. 11.
    Guo XS, Zahng YZ (1983) Quantitative TLC-densitometry of coumarins in Qin Pi (Fraxinus stylosa). Acta Pharm Sin 18:446–452Google Scholar
  12. 12.
    Wu JL, Fu GL, Zeng MY (1983) Studies on the quality and resource of the Chinese crude drug “Qin Pi” (Cortex fraxini). Chin J Pharm Anal 3:12–18Google Scholar
  13. 13.
    Brandt RB, Brandt ME, April ME (1983) Inhibitors of glyoxalase I in vitro. Biochem Med 29:385–391PubMedCrossRefGoogle Scholar
  14. 14.
    Sekiya K, Okuda H, Arichi S (1982) Selective inhibition of platelet lipoxygenase by esculetin. Biochim Biophys Acta 713:68–72PubMedGoogle Scholar
  15. 15.
    Neichi T, Koshihara Y, Murota T (1983) Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis. Biochim Biophys Acta 753:130–132PubMedGoogle Scholar
  16. 16.
    Panossian AG (1984) Inhibition of arachidonic acid 5-lipoxygenase of human polymorphonuclear leukocytes by esculetin. Biomed Biochim Acta 43:1351–1355PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Weici Tang
    • 1
  • Gerhard Eisenbrand
    • 1
  1. 1.Lebensmittelchemie und UmwelttoxikologieUniversität KaiserslauternKaiserslauternGermany

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