Skip to main content
SpringerLink
Log in
Book cover

Sandostatin® in the Treatment of Acromegaly pp 141–143Cite as

Long-Term Therapy of Acromegaly with SMS 201–995 (Sandostatin®)

  • Conference paper

  • 42 Accesses

Abstract

SMS 201–995 (Sandostatin®), a long-acting analogue of somatostatin, has been shown to be effective in lowering growth hormone (GH) levels in patients with acromegaly [1, 2]. Suppression of GH levels persists for 6 to 8 h and a treatment schedule of two or three daily injections is required to maintain optimum suppression. In the present study, 2 patients who had been unsuccessfully treated by surgery or surgery and pituitary irradiation were treated with Sandostatin for 12 to 18 months and clinical and laboratory parameters were followed to determine the efficacy of treatment.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Ch’ng JLC, Sandler LM, Kraenzlin ME, Burrin JM, Joplin GF, Bloom SR (1985) Chronic treatment of acromegaly with a long-acting somatostatin analogue. Br Med J 290: 284–285

    Article  Google Scholar 

  2. Lamberts SWJ, Oosterman R, Neufeld M, Del Pozo E (1985) The somatostatin analogue SMS 201-995 induced long-acting inhibition of growth hormone secretion without rebound hypersecretion in acromegalic patients. J Clin Endocrinol Metab 60: 1161–1165

    Article  CAS  PubMed  Google Scholar 

  3. Richmond W, Seviour PW, Teal TK, Elkeles RS (1987) Analgesic effect of somatostatin analogue (octreotide) in headache associated with pituitary tumours. Br Med J 295: 247–248

    Article  Google Scholar 

  4. Sandler LM, Burrin JM, Williams G, Joplin GF, Can DH, Bloom SR (1987) Effective long-term treatment of acromegaly with a long-acting somatostatin analogue (SMS 201995). Clin Endocrinol 26: 85–95

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, University of Toronto, Toronto, Ontario, Canada

    D. Killinger & J. Gonzalez

Authors
  1. D. Killinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Gonzalez
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Rotterdam, University Hospital, Dijkzigt, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands

    Steven W. J. Lamberts M.D.

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag, Berlin Heidelberg

About this paper

Cite this paper

Killinger, D., Gonzalez, J. (1988). Long-Term Therapy of Acromegaly with SMS 201–995 (Sandostatin®). In: Lamberts, S.W.J. (eds) Sandostatin® in the Treatment of Acromegaly. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73694-0_22

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73694-0_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73696-4

  • Online ISBN: 978-3-642-73694-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation