Autonomic Mechanisms in Cardiac Rhythm and Arrhythmias

  • W. Spinelli
  • M. R. Rosen
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 89)


Our purpose in this chapter is to review the cellular electrophysiologic effects of autonomic stimulation, and to demonstrate its complexity in two ways: by describing the changes in cardiac autonomic interactions that occur with growth and development, and by describing how autonomic mediators modulate cardiac arrhythmias.


Vagal Stimulation Action Potential Duration Purkinje Fiber Early Afterdepolarizations Cardiac Purkinje Fiber 
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© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • W. Spinelli
  • M. R. Rosen

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