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Interference of Tunicamycin-Induced Staphylococcal Lectin Dysfunction with Specific Adherence Mechanisms and Immune Responses

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The Influence of Antibiotics on the Host-Parasite Relationship III

Abstract

Staphylococcus saprophyticus is a coagulase-negative, novobiocin-resistant staphylococcus which is a frequent cause of urinary tract infections, especially in young women [7], Infection with this microorganism may also involve the upper urinary tract and reduce the concentration capacity of the kidney [5]. S. saprophyticus has been shown to adhere in greater numbers to uroepithelial cells and periurethral cells than to other types of cells, e.g., skin and buccal cells [3]. Accordingly, this microorganism is not known as a human pathogen in organ systems other than the urogenital tract [4].

This study was supported by the Deutsche Forschungsgemeinschaft

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References

  1. Beuth J, Ko HL, Schroten H, Sölter J, Uhlenbruck G, Pulverer G (1987) Lectin mediated adhesion of S. pneumoniae and its specific inhibition. Zbl Bakt Hyg [A] 265:160–168

    CAS  Google Scholar 

  2. Beuth J, Ko HL, Pulverer G (1988) The role of staphylococcal lectins in human granulocyte stimulation. Infection 16:46–48

    Article  PubMed  CAS  Google Scholar 

  3. Colleen S, Hovelius B, Wislander A, Mardh PA (1979) Surface properties of S. saprophyticus and S. epidermidis as studied by adherence tests and two-polymer, aqueous phase systems. Acta Pathol Microbiol Scand [B]87:321–328

    CAS  Google Scholar 

  4. Gunnarson A, Mardh PA, Lundblad A, Svenson S (1984) Oligosaccharide structures mediating agglutination of sheep erythrocytes by S. saprophyticus. Infect Immun 45:41–46

    Google Scholar 

  5. Hovelius B, Mardh PA, Bygren P (1979) Urinary tract infections caused by Staphylococcus saprophyticus. J Urol 122:645–647

    PubMed  CAS  Google Scholar 

  6. Irimura T, Gonzales R, Nicolson GL (1981) Effects of tunicamycin on B 16 metastatic melanoma cell surface glycoproteins. Cancer Res 41:3411–3418

    PubMed  CAS  Google Scholar 

  7. Jordan PE, Iravani A, Richard GA, Baer H (1980) Urinary tract infection caused by Staphylococcus saprophyticus. J Infect Dis 142:510–515

    Article  PubMed  CAS  Google Scholar 

  8. Kloos WE, Schleifer KH (1975) Simplified scheme for routine identification of human Staphylococcus species. J Clin Microbiol 1:82–88

    PubMed  CAS  Google Scholar 

  9. Pulverer G, Roszkowski W, Ko HL, Roszkowski K, Jeljaszewicz J (1986) Tierexperimentelle Untersuchungen zur Beeinflussung des Immunsystems durch Ofloxacin. Infection 14:40–44

    Article  Google Scholar 

  10. Teti G, Chiofalo MS, Tomasello F, Fava C, Mastroeni P (1987) Mediation of S. saprophyticus adherence to uroepithelial cells by lipoteichoic acid. Infect Immun 55:839–842

    PubMed  CAS  Google Scholar 

  11. Uhlenbruck G (1987) Bacterial lectins: mediators of adhesion. Zbl Bakt Hyg [A]263:497–508

    CAS  Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Beuth, J., Ko, H.L., Pfeiffer, R., Yassin, A., Ohshima, Y., Pulverer, G. (1989). Interference of Tunicamycin-Induced Staphylococcal Lectin Dysfunction with Specific Adherence Mechanisms and Immune Responses. In: Gillissen, G., Opferkuch, W., Peters, G., Pulverer, G. (eds) The Influence of Antibiotics on the Host-Parasite Relationship III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73653-7_5

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  • DOI: https://doi.org/10.1007/978-3-642-73653-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73655-1

  • Online ISBN: 978-3-642-73653-7

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