Effects of Glycopeptide and Lipopeptide Antibiotics on Granulocyte Function In Vitro

  • F. Schumacher-Perdreau
  • E. Schell-Frederick
  • G. Peters
  • G. Pulverer
Conference paper


Vancomycin and the newly developed teicoplanin are glycopeptide antibiotics with high activity against gram-positive bacteria, especially staphylococci and streptococci [8]. LY 146032 is a new cyclic polypeptide antibiotic containing a fatty acid moiety [3]. Similar to vancomycin and teicoplanin, the new cyclic lipopeptide demonstrates excellent activity against a broad range of gram-positive bacteria including methicillin-resistant strains of S. aureus and S. epidermidis [9].


Time Trace Fatty Acid Moiety Glycopeptide Antibiotic Opsonized Zymosan Human PMNs 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • F. Schumacher-Perdreau
    • 1
  • E. Schell-Frederick
    • 2
  • G. Peters
    • 1
  • G. Pulverer
    • 2
  1. 1.Institute of HygieneUniversity of KölnKöln 41Federal Republic of Germany
  2. 2.Department of Medicine IUniversity of KölnKöln 41Federal Republic of Germany

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