Characterization of T-Lymphocytes Cultured from Human Endomyocardial Biopsies

  • J. T. Fallon
  • I. Stamenkovic
  • D. M. Frisman
  • C. Leary
  • I. Palacios
  • J. T. Kurnick

Abstract

Myocarditis is often characterized by a lymphocytic inflammatory infiltrate in myocardial tissue. However, human myocarditis has neither a definitive etiologic agent nor a well-characterized pathogenesis [1]. Previous investigations of clinical myocarditis have centered around potential viral etiologies and the humoral immune aspects of the acute disease and its possible sequelae, namely dilated cardiomyopathy [2, 3, 4]. A few investigations have examined circulating T lymphocytes in patients with dilated cardiomyopathy [5, 6] while others have applied immunohistochemical techniques to characterize the inflammatory infiltrates in endomyocardial biopsies of myocarditis [7, 8, 9].

Keywords

Toxicity Arthritis Phenol Adenocarcinoma Recombination 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. T. Fallon
    • 1
  • I. Stamenkovic
    • 1
  • D. M. Frisman
    • 1
  • C. Leary
    • 1
  • I. Palacios
    • 1
  • J. T. Kurnick
    • 1
  1. 1.Department of Pathology, Department of Molecular Biology, Immunopathology Unit and Cardiac UnitMassachusetts General HospitalBostonUSA

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