Characterization of T-Lymphocytes Cultured from Human Endomyocardial Biopsies
Myocarditis is often characterized by a lymphocytic inflammatory infiltrate in myocardial tissue. However, human myocarditis has neither a definitive etiologic agent nor a well-characterized pathogenesis . Previous investigations of clinical myocarditis have centered around potential viral etiologies and the humoral immune aspects of the acute disease and its possible sequelae, namely dilated cardiomyopathy [2, 3, 4]. A few investigations have examined circulating T lymphocytes in patients with dilated cardiomyopathy [5, 6] while others have applied immunohistochemical techniques to characterize the inflammatory infiltrates in endomyocardial biopsies of myocarditis [7, 8, 9].
KeywordsDilate Cardiomyopathy Endomyocardial Biopsy Viral Myocarditis Lymphocyte Clone Lauryl Sarcosinate
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