On the Fine Structural Differential Diagnosis of Primary and Metastatic Lymph Node Tumors with Special Reference to the Nucleus

  • I. Valkov
Conference paper

Abstract

A great deal of research on the use of transmission electron microscopy (TEM) for tumor typing, e.g., for revealing tumor histogenesis, has occurred in the last 20 years and many publications, including general reviews, have appeared (Bern-hard 1969; Ghadially 1975; Reichlin et al. 1981; Krustev et al. 1982; Denk 1987). As a rule, the use of cytoplasmic features for diagnostic purposes has been stressed.

Keywords

Lymphoma Leukemia Adenocarcinoma Citrate Cortisol 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bernhard W (1969) Ultrastructure of cancer cells. In: Lima de Faria A (ed) Handbook of molecular cytology. North-Holland, Amsterdam, pp 688–715Google Scholar
  2. Cervera J, Almar M, Martinez A, Renau-Piqueras J (1983) Nuclear alterations induced by cadmium chloride and L-canavaline in HeLa S3 cells. Accumulation of perichromatin granules. J Ul-trastruct Res 82: 241–263CrossRefGoogle Scholar
  3. Cervera J, Baguena-Cervellera R, Martinez A (1985) The effect of zink chloride on the ribonucleoprotein structures in Hep2 cells. Accumulation of perichromatin granules. J Ultrastruct Res 93: 129–137PubMedCrossRefGoogle Scholar
  4. Denk H (1987) Immunological heterogeneity of malignant tumors. Pathol Res Pract 182: 483Google Scholar
  5. Dupuy-Coin A-M, Bouteille M (1975) Protein renewal in nuclear bodies, as studied by quantitative ultrastructural autoradiography. Exp Cell Res 90: 111–118PubMedCrossRefGoogle Scholar
  6. Ghadially FN (1975) Ultrastructural pathology of the cell. Butterworths, London, pp 1–91Google Scholar
  7. Goessens G (1984) Nucleolar structure. Int Rev Cytol 87: 107–158PubMedCrossRefGoogle Scholar
  8. Jordan EG (1984) Nucleolar nomenclature. J Cell Sci 67: 217–220PubMedGoogle Scholar
  9. Krustev L, Valkov I, Raitchev R, Prokopanov C (1982) Ultrastructural basis of pathology (in Bulgarian). Medizina i Fizkultura, Sofia, BulgariaGoogle Scholar
  10. Moyne G, Nash E, Puvion E (1977) Perichromatin granules in isolated rat hepatocytes treated with cortisol and cyclohexamide. Biol Cell 30: 5–16Google Scholar
  11. Reichlin NT, David H, Lapis K (1981) Ultrastructure of tumors in man (in Russian). Meditsina, Moskva, pp 13–20Google Scholar
  12. Smetana K, Bush H (1974) The nucleolus and nucleolar DNA. In: Bush H (ed) The cell nucleus. Academic, New York, pp 75–147Google Scholar
  13. Valkov I, Vassilev N (1977) Comparative morphologic and morphometric study on the perichromatin granules in normal and tumor lymph node cells. C R Acad Bulg Sci 30: 1347–1350Google Scholar
  14. Valkov I, Radeva V, Roussev G (1982) Nuclear ultrastructure of the newt’s neuroepithelial cells after treatment with embryoactive substances. Verh Anat Ges 76: 237–238Google Scholar
  15. Valkov I, Topov J, Vassilev N (1984) Nuclear ribonucleoprotein structures in malignancy. Proceedings, 13th European congress on cytology, Varna, Bulgaria, Sept 27–29, p 204Google Scholar
  16. Valkov I, Popov A, Goranova I (1987) On the complex approach in the differential diagnosis between primary and metastatic lymph node tumors. Pathol Res Pract 182 (4): 570–571Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • I. Valkov

There are no affiliations available

Personalised recommendations