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Effects of Sucrose Meal on Insulin Requirement in IDDM and its Modulation by Acarbose

  • J.-L. Chiasson
Conference paper

Abstract

We have studied in patients with insulin-dependent diabetes mellitus (IDDM) the effects of a sucrose meal on glucose gut absorption, glucose turnover, insulin requirement, and the modulation of the latter by a disaccharidase inhibitor, acarbose. Each subject (n = 5) was studied after an overnight fast during a sucrose meal of 50, 75 and 100 g with and without acarbose. Normoglycemia was maintained by the artificial pancreas. In three subjects gut absorption and glucose turnover were measured during the 75-g sucrose load.

Keywords

Diabetes Mellitus Blood Glucose Glucose Production Insulin Requirement Plasma Glucagon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J.-L. Chiasson
    • 1
  1. 1.IRCMMontrealCanada

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