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Effects of Sucrose Meal on Insulin Requirement in IDDM and its Modulation by Acarbose

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Acarbose for the Treatment of Diabetes Mellitus
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Abstract

We have studied in patients with insulin-dependent diabetes mellitus (IDDM) the effects of a sucrose meal on glucose gut absorption, glucose turnover, insulin requirement, and the modulation of the latter by a disaccharidase inhibitor, acarbose. Each subject (n = 5) was studied after an overnight fast during a sucrose meal of 50, 75 and 100 g with and without acarbose. Normoglycemia was maintained by the artificial pancreas. In three subjects gut absorption and glucose turnover were measured during the 75-g sucrose load.

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© 1988 Springer-Verlag Berlin Heidelberg

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Chiasson, JL. (1988). Effects of Sucrose Meal on Insulin Requirement in IDDM and its Modulation by Acarbose. In: Creutzfeldt, W. (eds) Acarbose for the Treatment of Diabetes Mellitus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73583-7_58

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  • DOI: https://doi.org/10.1007/978-3-642-73583-7_58

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-19145-2

  • Online ISBN: 978-3-642-73583-7

  • eBook Packages: Springer Book Archive

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