Regulation of Catecholamine Development

  • G. M. Jonakait
  • I. B. Black
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 90 / 2)

Abstract

How does the mature, fully-differentiated nervous system develop from its embryonic, undifferentiated precursors? This question, posed a century ago by classical embryologists, remains the central issue of contemporary developmental neurobiology. Even partial answers would begin to define the mechanisms which govern normal growth, development and aging of the nervous system. Moreover, such information may help to define the molecular pathogenesis of developmental and degenerative neurological disorders and the events which trigger transformation of normal neurons into their neoplastic counterparts, including pheochromocytomas and neuroblastomas.

Keywords

Dopamine Testosterone Noradrenaline Neurol Fibril 

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© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • G. M. Jonakait
  • I. B. Black

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