A depressive syndrome with its typical association of psychomotor retardation, anxiety, distortion of mood, disillusionment regarding the future, and lack of self-confidence with guilt feelings, is well-known to the medical profession. For the psychiatrist it is evident that the depressive syndromes reflect a multitude of mental disorders where, as in all other fields of medicine, a variety of background factors may be assigned etiological or symptomatological importance. The layman’s insight and convictions on the relationships between etiology and depressive mood disorders are, however, often very distant from the physiological realities reflected by clinical experience and research in the field. It is therefore urged that our image of depression involve a search for biological correlates to this group of disorders. Whatever pathogenic factors may be imagined in the individual case, the biopathological process remains the crossroads for diagnostic and basic therapeutic work.
KeywordsNuclear Magnetic Resonance Cerebral Blood Flow Affective Disorder Regional Cerebral Blood Flow Depressive Syndrome
Unable to display preview. Download preview PDF.
- Baxter LR, Maziotta JC, Phelps ME, Schwartz JM, Gerner RH (1985) Local cerebral glucose metabolism in affective disorders. Brain 85: 303–307 (Abstract)Google Scholar
- Margulis AR, Higgins CB, Kaufman L, Crooks LE (eds) (1983) Clinical magnetic resonance imaging. Radiology Research and Education FoundationGoogle Scholar
- Silverskiöld P, Gustafson L, Risberg J, Rosén I (1985) EEG and rCBF related to clinical outcome: acute and late effects. J Cereb Blood Flow Metab 5 [Suppl 1]: 187–188Google Scholar