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Reproductive and Endocrine Gonadal Capacity with and without GnRH Analogue Application During Chemotherapy in Patients Treated for Testicular Cancer

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LH-RH Agonists in Oncology

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Abstract

Since the introduction of aggressive chemotherapy, irradiation and bone marrow transplantation, long-lasting remissions and cures have been achieved in patients with certain types of neoplastic diseases. With this therapeutic success, late side effects may become clinically significant in long-term survivors. The acute and chronic toxicity of cytotoxic drugs in patients treated for testicular cancer is well known for most organs. Only limited data is available about endocrine and reproductive gonadal injury after PVB chemotherapy with cis-platinum, vinblastine, and bleomycin (Lange et al. 1983; Drasga et al. 1983; Johnson et al. 1984; Fossa et al. 1985; Kreuser et al. 1986).

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Authors
  1. E.-D. Kreuser
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  2. W. D. Hetzel
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Editors and Affiliations

  1. Innere Klinik und Poliklinik Westdeutsches Tumorzentrum, Universitätsklinikum Essen, Hufelandstr. 55, D-4300, Essen 1, Federal Republic of Germany

    Klaus Höffken

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© 1988 Springer-Verlag Berlin Heidelberg

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Kreuser, ED., Hetzel, W.D. (1988). Reproductive and Endocrine Gonadal Capacity with and without GnRH Analogue Application During Chemotherapy in Patients Treated for Testicular Cancer. In: Höffken, K. (eds) LH-RH Agonists in Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73530-1_10

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  • DOI: https://doi.org/10.1007/978-3-642-73530-1_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73532-5

  • Online ISBN: 978-3-642-73530-1

  • eBook Packages: Springer Book Archive

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