Suppressive Effect of Interferon Alpha-2b on Hemopoietic Progenitor Cells in Patients with Chronic Myelogenous Leukemia

  • U. B. Wandl
  • O. Kloke
  • B. Opalka
  • N. Niederle
Conference paper


The constitution and maintenance of normal hemopoiesis depends on the continuous proliferation and differentiation of hemopoietic stem cells and progenitor cells. The best-studied of these precursor cells are the stem cell-like progenitors (CFU-GEMM), the early erythroid progenitors (BFU-E), the granulocytic progenitors (CFU-C), and the megakaryocytic progenitors (CFU-M) [2, 4]. The levels of these colony forming cells reflect the functional capacity of hemopoiesis.


Progenitor Cell Chronic Myeloid Leukemia Chronic Myelogenous Leukemia Chronic Myeloid Leukemia Patient Erythroid Progenitor 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • U. B. Wandl
  • O. Kloke
  • B. Opalka
  • N. Niederle

There are no affiliations available

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