Cell Biology of Tumor Metastasis Formation

  • V. Schirrmacher
Conference paper


It cannot be denied that progress has been made in the surgical techniques applied in the removal of local tumors or solitary metastases. The subject of this meeting, however, reflects the feelings that surgery is not always useful and that the surgeon’s arch-enemies are micrometastases, which frequently prevent an operation from being successful and which determine the fate of the majority of patients. As little is known for sure about the basic processes involved in the formation of tumor metastases, and because surgical intervention can both inhibit and promote the process, it is of course important to familiarize ourselves with the main basic aspects of the cell biology in metastasis; most of our information is derived from experimental studies.


Metastasis Formation Solitary Metastasis Tumor Variant Single Tumor Cell Gene Regulation Variant 
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© Springer-Verlag Berlin Heidelberg 1989

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  • V. Schirrmacher

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