Advertisement

First Experiences in Würzburg of Interstitial Low-Dose Afterloading for Breast-Conserving Therapy with the Microselectron

  • K. Rotte
  • E. Löffler
Conference paper

Abstract

In Germany, manual interstitial brachytherapy was abandoned for many years due to the radiation hazard associated with it. There is now a return of this mode of treatment with the introduction of remote-controlled afterloading machines [4, 7–9, 14, 15]. Compared with teletherapy, two great advantages favor contact therapy. One is that, for the same reference volume, the integral dose within the target is higher. The other advantage is that the treatment volume can be kept smaller. In breast-conserving therapy, this enables us to administer a high dose within the tumor bed and simultaneously spare skin and lung.

Keywords

Reference Volume Arch Gynecol Obstet Source Assembly Iridium Wire Spare Skin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Barendsen GW (1982) Dose fractionation, dose rate and iso-effect relationships for normal tissue response. Int J Radiat Oncol Biol Phys 8: 1981PubMedCrossRefGoogle Scholar
  2. 2.
    Dutreix A, Marinello G, Wambersie A (1982) Dosimétrie en curiethérapie. Masson, ParisGoogle Scholar
  3. 3.
    Hall EJ (1972) Radiation dose-rate: a factor of importance in radiobiology and radiotherapy. Br J Radiol 45: 81PubMedCrossRefGoogle Scholar
  4. 4.
    Jacobs H, Teusch P, Schleppi V, Schmieder A, Moncke G (1984) Interstitielle Brachytherapie - Erste Erfahrungen mit 192-Iridium in der Kurzzeittherapie. Strah-lentherapie 160: 8Google Scholar
  5. 5.
    Kellerer AM, Rossi HH (1972) The theory of dual radiation action. Curr Top Radiat Res Q 8: 85Google Scholar
  6. 6.
    Laarse R (1985) Treatment planning of interstitial radiotherapy (MPS) with the selectron treatment planning system. In: Mould RF (ed) Brachytherapy 1984. Nucletron, Leersum, p 286Google Scholar
  7. 7.
    Löffler E, Rotte K (1987) Die Würzburger Methode der ferngesteuerten interstitiellen low-dose-rate Brachytherapie bei der brusterhaltenden Behandlung des Mammakar-zinoms. Arch Gynecol Obstet 242: 301–303CrossRefGoogle Scholar
  8. 8.
    Löffler E, Sauer O (1987) 3-D Rekonstruktion von Brust-Implantaten zur Applika-tionskontrolle und Bestrahlungsplanung mittels isozentrischer stereoskopischer Röntgenaufnahmen (ISR) unter Berücksichtigung einer ferngesteuerten interstitiellen Nachlademethode. Strahlentherapie, (in press)Google Scholar
  9. 9.
    Löffler E, Sauer O, Rotte K (1986) Interstitielle Low-Intensity Afterloading-Therapie mit 192Ir-Drähten. In: von Klitzing L (ed) Medizinische Physik 1986. DGMP, Lübeck, p 433Google Scholar
  10. 10.
    Meertens H, Bartelink H (1985) First experience with the microselectron in breast conserving therapy implants. In: Mould RF (ed) Brachytherapy 1984. Nucletron, Leersum, p 271Google Scholar
  11. 11.
    Pierquin B, Baillet F, Wilson JF (1976) Radiation therapy in the management of primary breast cancer. A J R 127: 645PubMedGoogle Scholar
  12. 12.
    Pierquin B, Dutreix A, Paine CH, Chassagne D, Marinello G, Ash D (1978) The Paris system in interstitial radiation therapy. Acta Radiol [Oncol] 17: 33CrossRefGoogle Scholar
  13. 13.
    Pierquin B, Owen R, Maylin C, Otmezguine Y, Raynal M, Mueller W, Haunoun S (1980) Radical radiation therapy of breast cancer. Int J Radiat Oncol Biol Phys 6: 17PubMedGoogle Scholar
  14. 14.
    Rotte K, Löffler E (1986) Strahlentherapeutische Möglichkeiten bei der Behandlung des primär operablen Mammakarzinoms. Gynäkol Prax 10: 695Google Scholar
  15. 15.
    Schulz U, Busch M, Bormann U (1984) Interstitial high doserate brachytherapie: Principle, practice and first clinical experiences with a new remote-controlled after- loading system using Ir-192. Int J Radiat Oncol Biol Phys 10: 915PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • K. Rotte
  • E. Löffler

There are no affiliations available

Personalised recommendations