Electrophysiological Characteristics of Peptidergic Nerve Terminals Correlated with Secretion

  • E. L. Stuenkel
  • I. M. Cooke
Part of the Current Topics in Neuroendocrinology book series (CT NEUROENDOCRI, volume 9)


This article reviews studies correlating electrical with secretory activity of a peptidergic neurosecretory system of crabs known as the X-organ — sinus gland system (XOSG). Justification for giving such attention to an invertebrate model derives from the unique observations obtainable by reason of the relatively huge size of axon terminals (in certain species) and the discrete anatomical segregation of the system. These permit (1) experimentation on an intact, purely peptidergic neurosecretory system removed to a chamber, (2) simultaneous intracellular recording from electrodes placed under visual control into somata and terminals, and (3) monitoring of secretion separately from both somata and terminal regions while recording. The XOSG is analogous to the vertebrate hypothalamic-neuro-hypophysial system in function as well as in those details of physiological mechanisms for which comparable information is available. Generalizability of the information obtainable only from the XOSG to other neurosecretory systems thus seems likely.


Neurosecretory Cell Fiddler Crab Neurosecretory System Sinus Gland Medulla Terminalis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • E. L. Stuenkel
    • 1
  • I. M. Cooke
    • 2
  1. 1.Department of PhysiologyUniversity of MichiganAnn ArborUSA
  2. 2.Békésy Laboratory of NeurobiologyUniversity of HawaiiHonoluluUSA

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