Stimulus-Secretion Coupling in the Oxytocin System

  • A. J. S. Summerlee
  • L. J. Parry
Part of the Current Topics in Neuroendocrinology book series (CT NEUROENDOCRI, volume 9)


One of the fundamental processes in the functioning of magnocellular neurones is the mechanism of stimulus-secretion coupling, that is the translation of electrical activity of the neurones into the release of precise quantities of neurosecretory product, and we shall be addressing this concept in the oxytocin system in the present chapter. However, we shall broaden the definition to describe the types and modes of stimulation that are responsible for the secretion of oxytocin and its appearance in the blood. It is necessary to start the chapter with a brief review of the biochemistry, anatomy and physiology of the oxytocin system and to explain how it is possible to take recordings from identified oxytocin neurones in the hypothalamus.


Compound Action Potential Supraoptic Nucleus Neurosecretory Granule Magnocellular Neurone Milk Ejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • A. J. S. Summerlee
  • L. J. Parry

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