Granulocyte Adherence in Patients Undergoing Cardiac Surgery Under Cardiopulmonary Bypass

  • P. Kinnaert
  • N. Van Geertruyden
  • B. Bournonville
  • J. Bastenier
  • J. L. Leclerc
Conference paper

Abstract

Inflammation is the first line of defense of the body against infection. Granulocyte adherence (GA) is an important component of inflammatory reactions. It is profoundly altered by complement activation. Therefore, it seemed interesting to study GA in patients undergoing cardiac surgery under cardiopulmonary bypass (CPB), a procedure known to activate the complement cascade.

Keywords

Aspirin Heparin Prostaglandin Nylon Mannitol 

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References

  1. 1.
    Christou NV, Meakins JL (1979) Neutrophil function in anergic surgical patients: neutrophil adherence and chemotaxis. Ann Surg 190: 557–564PubMedCrossRefGoogle Scholar
  2. 2.
    Mac Gregor RP, Spagnuolo PJ, Lentnek AL (1974) Inhibition of granulocyte adherence by ethanol, prednisone and aspirin measured with an assay system. N Engl J Med 291: 642–646CrossRefGoogle Scholar
  3. 3.
    Mac Gregor RP, Marcarak EJ, Kefalides NA (1978) Comparative adherence of granulocytes to endothelial monolayers and nylon fibers. J Clin Invest 61: 687–702CrossRefGoogle Scholar

Copyright information

© Springer-Verlag, Berlin Heidelberg 1989

Authors and Affiliations

  • P. Kinnaert
  • N. Van Geertruyden
  • B. Bournonville
  • J. Bastenier
  • J. L. Leclerc

There are no affiliations available

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