Abstract
Sepsis and trauma-related organ failure is intimately related to granulocyte functions. Granulocytes protect the organism against bacterial invasion but may also cause endothelial damage due to the release of reactive oxygen intermediates and proteolytic enzymes. The purpose of this study was the analysis of cell-biochemical parameters of granulocytes by flow cytometry and the use of the multifunctional parameter pattern for the prediction of sepsis- and trauma-related pulmonary and cardiovascular organ failure.
This work was supported by DFG SFB 0207, project G6.
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Rothe, G., Kellermann, W., Valet, G. (1989). Flow Cytometric Analysis of Phagocytosis, Respiratory Burst, Intracellular pH, and Cytosolic Free Calcium of Granulocytes of Post-traumatic and Septic Patients. In: Faist, E., Ninnemann, J.L., Green, D.R. (eds) Immune Consequences of Trauma, Shock, and Sepsis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73468-7_29
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DOI: https://doi.org/10.1007/978-3-642-73468-7_29
Publisher Name: Springer, Berlin, Heidelberg
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