Comparison of Pain Threshold as Assessed by Tooth Pulp Stimulation in Normotensives with Different Hypertensive Hereditary Backgrounds and in Borderline and Established Hypertensives

  • S. Ghione
  • C. Rosa
  • L. Mezzasalma
  • E. Panattoni


Several lines of evidence suggest a relationship between central mechanisms involved in arterial blood pressure and pain regulation. Anatomical and physiological studies have shown that the brain stem areas participating in the regulation of blood pressure and those involved in the modulation of pain transmission are closely associated or may even partially overlap [1–3]. In addition, the results of recent studies have demonstrated an association between increased blood pressure (BP) levels and decreased pain perception. A hypoalgesic behaviour has been repeatedly observed in the rat with experimental or genetic hypertension [4–10] and equivalent findings have been reported in human hypertension [11–12]. In order to gain a better insight into this aspect, tolerance to pain was assessed in a large group of normotensives (NT) and hypertensives (HT) by means of a non invasive tooth pulp stimulation test.


Pain Threshold Pain Perception Pain Sensitivity Dental Pulp Tooth Pulp 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • S. Ghione
    • 1
  • C. Rosa
    • 1
  • L. Mezzasalma
    • 1
  • E. Panattoni
    • 1
    • 2
  1. 1.CNR Institute of Clinical PhysiologyItaly
  2. 2.Dental ClinicUniversity of PisaPisaItaly

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