Effects of Hemorrhagic Shock on Plasma Met-enkephalin, Vasopressin, Catecholamines, and Cardiovascular Functions in Intact and Adrenalectomized Dogs

  • T. Kimura
  • M. Inoue
  • K. Matsui
  • K. Ota
  • M. Shoji
  • K. Iitake
  • K. Yoshinaga
Conference paper

Abstract

It is well known that enkephalins in the brain, unlike the adrenal gland and sympathetic nervous system, coexist with vasopressinergic neurons in the hypothalamoneuro- hypophyseal system (Martin and Voigt 1981; Martin et al. 1983). Moreover, the enkephalin contents of this region have been reported to decrease in dehydrated rats and/or Brattleboro rats with a genetic defect in vasopressin synthesis (Marina et al. 1977; Rossier et al. 1979). Furthermore, it has recently been documented that plasma enkephalin-like immunoreactivity is increased in animals with endotoxic or hemorrhagic shock (Evans et al. 1984; Lang et al. 1982), reminiscent of vasopressin release in hypotensive shock (Share 1974).

Keywords

Catheter Heparin Dehydration Methionine Adrenaline 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • T. Kimura
    • 1
  • M. Inoue
    • 1
  • K. Matsui
    • 1
  • K. Ota
    • 1
  • M. Shoji
    • 1
  • K. Iitake
    • 1
  • K. Yoshinaga
    • 1
  1. 1.The Second Department of Internal MedicineTohoku University School of Medicine 1-1Seiryocho, Sendai 980Japan

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