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Effects of Hemorrhagic Shock on Plasma Met-enkephalin, Vasopressin, Catecholamines, and Cardiovascular Functions in Intact and Adrenalectomized Dogs

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Opioid Peptides and Blood Pressure Control
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Abstract

It is well known that enkephalins in the brain, unlike the adrenal gland and sympathetic nervous system, coexist with vasopressinergic neurons in the hypothalamoneuro- hypophyseal system (Martin and Voigt 1981; Martin et al. 1983). Moreover, the enkephalin contents of this region have been reported to decrease in dehydrated rats and/or Brattleboro rats with a genetic defect in vasopressin synthesis (Marina et al. 1977; Rossier et al. 1979). Furthermore, it has recently been documented that plasma enkephalin-like immunoreactivity is increased in animals with endotoxic or hemorrhagic shock (Evans et al. 1984; Lang et al. 1982), reminiscent of vasopressin release in hypotensive shock (Share 1974).

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© 1988 Springer-Verlag Berlin Heidelberg

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Kimura, T. et al. (1988). Effects of Hemorrhagic Shock on Plasma Met-enkephalin, Vasopressin, Catecholamines, and Cardiovascular Functions in Intact and Adrenalectomized Dogs. In: Stumpe, K.O., Kraft, K., Faden, A.I. (eds) Opioid Peptides and Blood Pressure Control. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73429-8_26

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  • DOI: https://doi.org/10.1007/978-3-642-73429-8_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-18935-0

  • Online ISBN: 978-3-642-73429-8

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