Theoretical Calculations of the Structures of Some Prostaglandins and Inhibitors of Lipoxygenase

  • J. Barker
  • C. Thomson


The methods of computational chemistry have now developed to the point where calculations of the structure and properties of molecules of biological importance can yield important information complementary to that obtained in experimental studies (Richards 1983). There are many recent reviews of these exciting developments (Narày-Szabó 1986; Beveridge and Jorgensen 1986), and the advent of sophisticated colour graphics displays has seen a mushrooming of applications to a wide range of problems, especially in pharmacology, where computer assisted drug design is of increasing importance (Venkataraghvan and Feldman 1985).


Arachidonic Acid Tumour Promotion Molecular Electrostatic Potential Arachidonic Acid Metabolism Arachidonic Acid Cascade 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. Barker
    • 1
  • C. Thomson
    • 1
  1. 1.NFCR Project, Department of ChemistryUniversity of St. AndrewsSt. AndrewsUK

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