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Theoretical Calculations of the Structures of Some Prostaglandins and Inhibitors of Lipoxygenase

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Eicosanoids, Lipid Peroxidation and Cancer

Abstract

The methods of computational chemistry have now developed to the point where calculations of the structure and properties of molecules of biological importance can yield important information complementary to that obtained in experimental studies (Richards 1983). There are many recent reviews of these exciting developments (Narày-Szabó 1986; Beveridge and Jorgensen 1986), and the advent of sophisticated colour graphics displays has seen a mushrooming of applications to a wide range of problems, especially in pharmacology, where computer assisted drug design is of increasing importance (Venkataraghvan and Feldman 1985).

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Authors and Affiliations

  1. NFCR Project, Department of Chemistry, University of St. Andrews, St. Andrews, KY16 9ST, UK

    J. Barker & C. Thomson

Authors
  1. J. Barker
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  2. C. Thomson
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Editor information

Editors and Affiliations

  1. Frauenklinik, Universitäts-Klinikum Steglitz, Hindenburgdamm 30, 1000, Berlin 45, Germany

    Santosh K. Nigam Ph.D., M.B., B.Ch.

  2. Department of Biology and Biochemistry, Brunel University, Uxbridge, Middlesex, UB8 3PH, UK

    David C. H. McBrien Ph.D.  & Trevor F. Slater Ph.D., D.Sc., M.D.(Hon.)  & 

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© 1988 Springer-Verlag Berlin Heidelberg

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Barker, J., Thomson, C. (1988). Theoretical Calculations of the Structures of Some Prostaglandins and Inhibitors of Lipoxygenase. In: Nigam, S.K., McBrien, D.C.H., Slater, T.F. (eds) Eicosanoids, Lipid Peroxidation and Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73424-3_13

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  • DOI: https://doi.org/10.1007/978-3-642-73424-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-18932-9

  • Online ISBN: 978-3-642-73424-3

  • eBook Packages: Springer Book Archive

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