Summary
Two genetically engineered bacteria were constructed by a patchwork assembly of cloned genes from different bacteria into Pseudomonas sp. strain B13. The engineered bacteria were able to degrade chlorinated and methylated benzoic acids which often exist simultaneously in industrial waste streams at concentrations which inhibit their degradation by indigenous microorganisms. The bacterial strains were shown to survive within a model aerobic sludge ecosystem and were able to degrade substituted benzoates that were present in ordinarily inhibitory combinations.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Keith, L.H. and Telliard, W.A. (1979). Environ. Sci. Technol. 13, 416–423
Ramos, J.L., Stolz, A., Reineke, W. and Timmis, K.N. (1986). Proc. Natl. Acad. Sci. USA. 83, 8467–8471
Ramos, J.L. and Timmis, K.N. (1987). Microbiol. Sci. 4, 228–237
Levin, M.A., Scidler, R., Borquin, A.W., Fowle, J.R. III and Barkay, T. (1987). Bio/Technology 5, 38–45
Jain, R.K., Sayler, G.S., Wilson, J.T., Houston, L. and Pacia, D. (1987). Appl. Environ. Microbiol. 53, 996–1002
Liang, L.N., Sinclair, J.L., Mailory, L.M. and Alexander, M. (1982). Appl. Environ. Microbiol. 44, 708–714
Xnackmuss, H.-J. (1983). in Biotechnology, eds. Phelps, C. F. and Clarke, P.H. (University Press, Cambridge), pp 173–190
Rojo, F., Pieper, D.H., Engesser, K.-H., Knackmuss, H.-J. and Timmis, K.N. (In press). Science
Reineke, W. and Knackmuss, H.-J. (1980). J. Bacteriol. 142, 467–473
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Dwyer, D.F., Rojo, F., Timmis, K.N. (1988). Bacteria with New Pathways for the Degradation of Pollutants and their Fate in Model Ecosystems. In: Klingmüller, W. (eds) Risk Assessment for Deliberate Releases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73419-9_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-73419-9_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-73421-2
Online ISBN: 978-3-642-73419-9
eBook Packages: Springer Book Archive