Skip to main content

The Application of Monoclonal Antibodies for the Definition of Genetic Markers of Human Red Cells

  • Conference paper
Advances in Forensic Haemogenetics

Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 2))

Abstract

Monoclonal antibodies have now been produced to the red cell antigens A, A1, B, A and B, M, N, D, LW, e, H, I, Lea, Leb, P, P1, K, k, LKE, Lub, T, Tn, Wrb, and MER 2.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anstee DJ (1983), The structure of the MN and Ss blood group antigens. Bio Bull 4: 318–321.

    Google Scholar 

  • Bird GWG, Wingham J (1970) N-acetyl neuraminic (sialic) acid and human blood group antigen structure. Vox Sang 18: 240–243.

    Article  PubMed  CAS  Google Scholar 

  • Bron D, Feinberg MB, Nelson NHT, Kaplan HS (1984) Production of human monoclonal IgG antibodies against Rhesus (D) antigen. Proc. Nat. Acad. Sci. USA 81: 3214–3217.

    Article  PubMed  CAS  Google Scholar 

  • Crawford DH, Barlow MJ, Harrison JF, Winger L, Huehns ER (1983) Production of human antibody to Rhesus D antigen. Lancet 1: 386–388.

    Article  PubMed  CAS  Google Scholar 

  • Dahr W, Uhlenbruck G, Knott H (1975) Immunochemical aspects of the MNSs-blood group system. J of Imm 2: 87–100.

    Article  Google Scholar 

  • Dahr W, Uhlenbruck G, Jansen E, Schmalish R (1977) Different N-terminal amino acids in the MN glycoprotein from MM and NN erythrocytes. Human Genet 35: 335–343.

    Article  CAS  Google Scholar 

  • Dahr W, Uhlenbruck G, Leikola J, Wagstaff W (1978) Studies on the membrane glycoprotein defect of En (a-) erythrocytes: III N-terminal amino acids of sialoglyoproteins from normal and En (a-) red cells. J of Imm 5: 117–123.

    Article  CAS  Google Scholar 

  • Fletcher A, Harbour C, Matthews M, de Zwart R, Ford D (1986) Blood grouping with monoclonal anti-N antibodies. Aus J of Exp Biol & Med Sci 64: 215–222.

    Article  Google Scholar 

  • Frazer RH, Munro AC, Williamson AR, Barrie EK, Hamilton EA, Mitchell R (1982) Mouse monoclonal anti-N. J of Immun 9: 295–302.

    Article  Google Scholar 

  • Greenwell P, Yates AD, Watkins WM (1979) Blood group A synthesising activity of the blood group B gene specified-3-galactosyl transferase. In Glyconjugates, eds R Schaur, P Boer, E Buddecke, MF Kramer. Vliegenthart and Wiegendt, Thieme, Stuttgart. 268–269.

    Google Scholar 

  • Hoppe AH (1979) Considerations in the selection of reagents. American Association of Blood Banks, Washington, Appendix 1, p 15.

    Google Scholar 

  • Kohler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256: 495–497.

    Article  PubMed  CAS  Google Scholar 

  • Lowe AD, Lennox E, Voak D (1984) A new monoclonal anti-A: culture supernatants with the performance of hyperimmune human reagents. Vox Sang 46: 29–35.

    Article  PubMed  CAS  Google Scholar 

  • Lowe AD, Green SM, Voak D et al (1986) A human-human monoclonal anti-D by direct fusion with a lymphoblastoid line. Vox Sang 51 : 212–216.

    Article  PubMed  CAS  Google Scholar 

  • Messeter L, Brodin T, Chester MA et al (1984) Mouse monoclonal antibodies with anti-A, anti-B and anti-A, B specificities; some superior to human polyclonal ABO reagents. Vox Sang 46: 185–194.

    Article  PubMed  CAS  Google Scholar 

  • Moore BPL (1984) Does knowledge of Du status serve a useful purpose. Vox Sang 46: 95–102.

    Article  Google Scholar 

  • Moore S, Chirnside A, Micklem LR et al (1984) A mouse monoclonal antibody with anti-A(B) specificity which agglutinates A cells. Vox Sang 47: 427–434.

    Article  PubMed  CAS  Google Scholar 

  • Nichols ME, Rosenfield RE, Rubinstein P (1985) Two blood group M epitopes disclosed by monoclonal antibodies. Vox Sang 49: 134–148.

    Article  Google Scholar 

  • Race RR, Sanger R (1975) Blood groups in Man. 6th edn. Blackwell Oxford, pp 189–193.

    Google Scholar 

  • Rubocki R, Milgrom F (1986) Reactions of murine monoclonal antibodies to blood group MN antigens. Vox Sang 51: 217–225

    Article  PubMed  CAS  Google Scholar 

  • Sacks S, Lennox E (1981) Monoclonal anti-B as a new source of blood typing reagents. Vox Sang 40: 99–104.

    Article  PubMed  CAS  Google Scholar 

  • Sonneborn HH, Uthemann H, Munro AC, Bruce M, Fraser RH, Inglis G (1984) Reactivity of monoclonal antibodies directed against blood group antigens M and N. Dev Biol Stand 57: 61–68.

    PubMed  CAS  Google Scholar 

  • Sonneborn HH, Ernst M (1987) Further characterisation and standardisation of mouse monoclonal antibodies reacting with M/N blood group antigens. Dev Biol Stand 67: 97–104.

    PubMed  CAS  Google Scholar 

  • Thompson KM, Melamed MD, Eagle K, et al (1986) Production of human monoclonal IgG and IgM antibodies with anti-D rhesus specificity using heterohybridomas. Imm 58: 157–160.

    CAS  Google Scholar 

  • Tippett P, Sanger R (1962) Observations on subdivisions of the Rh antigen D, Vox Sang 7: 9–13.

    Article  PubMed  CAS  Google Scholar 

  • Treacy M, Stroup M (eds) (1987) Proceedings of A scientific forum on blood grouping anti-A (murine monoclonal blend) Bioclone. Sept 1986, Raritan. Ortho Diagnostics DS1 – 346.

    Google Scholar 

  • Voak D (1986) Monoclonal antibodies: application to blood group serology. Labmed Aug/Sept: 27–31.

    Google Scholar 

  • Voak D, Lowe AD, Lennox E (1983) Monoclonal antibodies: ABO serology Bio Bull 4: 291–299.

    Google Scholar 

  • Voak D, Lennox E (1986) Monoclonal antibodies for laboratory aspects of transfusion practice. Progress in Transfusion Medicine 1: ed J. Cash, pp 1–18. Churchill Livingstone, Edinburgh.

    Google Scholar 

  • Voak D, Davies D, Beck M, Yates AD (1987) (to be published) The B(A) phenomenon: a monoclonal anti-A (MHO4) demonstrates traces of “A” on normal group B red cells. Vox Sang.

    Google Scholar 

  • Wasniowska K, Reichert CM, McGinniss MH et al (1985) Two monoclonal antibodies highly specific for the blood group N determinant. Glyconjugate J 2: 163–176.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Voak, D., Davies, D., Sonneborn, H., Moulds, J., Fletcher, A., Downie, D.M. (1988). The Application of Monoclonal Antibodies for the Definition of Genetic Markers of Human Red Cells. In: Mayr, W.R. (eds) Advances in Forensic Haemogenetics. Advances in Forensic Haemogenetics, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73330-7_56

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73330-7_56

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-18765-3

  • Online ISBN: 978-3-642-73330-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics