Skip to main content

Platelet Reactivity in Ergotamine Headache Compared to Migraine and Muscle Contraction Headache

  • Conference paper
Drug-Induced Headache

Part of the book series: Advances in Applied Neurological Sciences ((NEUROLOGICAL,volume 5))

  • 70 Accesses

Abstract

Enhanced platelet reactivity in migraine seems well established (Grotemeyer et al. 1983; Lechner et al. 1985). The basis for the observed change in platelet function is still unknown (Kruglak et al. 1984). Abnormal platelet reactivity could represent a side effect of migraine (Deshmuk and Meyer 1977), it could be a pure epiphenomenon (Rose 1985), or it may be an important step in the evolution of a migraine headache (Hannington et al. 1981).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ad hoc committee on classification of headache (1962) Classification of headache. Arch Neurol 6: 173–176

    Google Scholar 

  • Born GVR (1982) Die Rolle der Thrombozyten bei der Athero-und Thrombogenese. Rheinisch Westfälische Akademie der Wissenschaften Nr 295 Sitzung Vortrag N320. Westdeutscher Verlag, Opladen

    Google Scholar 

  • Deshmuk SV, Meyer JS (1977) Cyclic changes in platelet dynamics and the pathogenesis and prophylaxis of migraine. Postgrad Med 68,1:133–137

    Google Scholar 

  • Edvinsson L, Degueurce A, Duverger D, MacKenzie ET, Scatton B, Uddman R (1983) Coupling between cerebral blood flow and metabolism: a role for serotonin? In: MacKenzie ET (ed) Neurotransmitters and the cerebral circulation 2: 121–137

    Google Scholar 

  • Grotemeyer KH, Hofferberth B (1985) Zirkulierende Plättchenaggregate bei Patienten mit akuten ischämischen und sogenannten chronischen zerebrovaskulären Störungen. Dtsch Med Wochenschr 110: 256–259

    Article  PubMed  CAS  Google Scholar 

  • Grotemeyer KH, Viand R, Beykirch K (1983) Thrombozytenfunktion bei vasomotorischem Kopfschmerz und Migränekopfschmerz. Dtsch Med Wochenschr 106: 775–778

    Article  Google Scholar 

  • Hannington E, Jones R, Amess JAL, Wachowitz B (1981) Migraine a platelet disorder? Lancet II: 720–721

    Article  Google Scholar 

  • Hilton BP, Cumings JN (1972) 5-Hydroxytryptamine levels and platelet aggregation responses in subjects with acute migraine headache. J Neurol Neurosurg Psychiatry 35:505–509

    Article  PubMed  CAS  Google Scholar 

  • Kruglak L, Nathan I, Korczyn AD, Zolozov Z, Berginer V, Dvilansky A (1984) Platelet aggregability, disaggregability and serotonin uptake in migraine. Cephalalgia 4: 221–225

    Article  PubMed  CAS  Google Scholar 

  • Lechner H, Ott E, Fazekas E, Pilger E (1985) Evidence of enhanced platelet aggregation and platelet sensitivity in migraine patients. Cephalalgia 2: 89–91

    Google Scholar 

  • Miiller-Schweinitzer E (1978) Studies on the 5-HT receptor in vascular smooth muscle. In: Friedman AP, Granger ME, Critchley M (eds) Research and clinical studies in headache, headache today — an update by 21 experts, vol 6: 6–12. Karger, Basel

    Google Scholar 

  • Norris JW, Hatchinski VC, Cooper PW (1975) Changes in cerebral blood flow during migraine attack. Br Med J [Clin Res] 3: 676–677

    Article  CAS  Google Scholar 

  • Rose FC (1985) The role of platelets in migraine. Cephalalgia 2.83–85

    Google Scholar 

  • Saxena PR (1972) The effects of antimigraine drugs on the vascular responses by 5-hydroxytryptamine and related biogenic substances on the external carotid bed of dogs: possible pharmacological implications to their antimigraine action. Headache 12: 44–54

    Article  PubMed  CAS  Google Scholar 

  • Simrad D, Paulsen OB (1973) Cerebral vasomotor paralysis during migraine attack. Arch Neurol 29: 95–101

    Google Scholar 

  • Vanhoutte PM (1978) Heterogenity in vascular smooth muscle. In: Kaley G, Altura BM (eds) Microcirculation. University press, Baltimore, pp 181–309

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Grotemeyer, KH., Schlake, HP., Husstedt, I.W. (1988). Platelet Reactivity in Ergotamine Headache Compared to Migraine and Muscle Contraction Headache. In: Diener, HC., Wilkinson, M. (eds) Drug-Induced Headache. Advances in Applied Neurological Sciences, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73327-7_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73327-7_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73329-1

  • Online ISBN: 978-3-642-73327-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics