Abstract
The G proteins comprise a family of membrane-associated proteins that transduce extracellular signals such as hormones or photons into a diverse array of cellular responses. All these proteins bind and hydrolyze GTP, and GTP in turn regulates their interactions with signal detectors (cell surface receptors) and effectors (membrane-associated enzymes and ion channels). Each G protein utilizes a common GTP-dependent mechanism to transduce signals between unique sets of detector and effector elements.
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© 1986 Springer-Verlag Berlin Heidelberg
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Masters, S.B., Bourne, H.R. (1986). Role of G Proteins in Transmembrane Signaling: Possible Functional Homology with the ras Proteins. In: Kahn, P., Graf, T. (eds) Oncogenes and Growth Control. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73325-3_25
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DOI: https://doi.org/10.1007/978-3-642-73325-3_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-18760-8
Online ISBN: 978-3-642-73325-3
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