Abstract
One problem which is central to an understanding of both cellular growth control and the mechanism of hormone action is the nature of the signal pathway and, in particular, the identity of the second messenger molecules which trigger DNA synthesis. The main components of the signal pathways by which growth factors stimulate cell growth are shown in Fig. 1. The fact that different growth factors do not all act via the same mechanism suggests that there may be qualitatively different signal pathways. At some stage these pathways merge with each other, but the points of convergence are still obscure. The importance of understanding these pathways and their transduction mechanisms is underscored by recent findings which suggest that certain oncogenes encode proteins which participate in signal pathways.
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Berridge, M.J. (1986). Inositol Lipids and Cell Proliferation. In: Kahn, P., Graf, T. (eds) Oncogenes and Growth Control. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73325-3_20
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DOI: https://doi.org/10.1007/978-3-642-73325-3_20
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-18760-8
Online ISBN: 978-3-642-73325-3
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