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Smoking and Ulcer Healing — Role for Prostaglandins?

  • E. J. S. Boyd
  • K. G. Wormsley
Conference paper

Abstract

Cigarette smoking is causally related to duodenal ulcer (DU) and gastric ulcer (GU) disease: there is an increased incidence of DU [1] and GU [2] in patients who are smokers compared with non-smokers; there is a dose-response, in that the greater the number of cigarettes a patient smokes and the longer the history of smoking, the greater the relative risk of developing an ulcer [3]; and cigarette smoking is associated with pathophysiological abnormalities which may predispose to or aggravate duodenal or gastric ulcer disease (Table 1). In addition, cigarette smoking is associated with a slower rate of healing of duodenal and gastric ulcers during treatment with a variety of non-prostaglandin ulcer-healing drugs or placebo [4].

Keywords

Cigarette Smoking Duodenal Ulcer Gastric Ulcer Gastric Mucosal Blood Flow Duodenal Ulcer Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • E. J. S. Boyd
  • K. G. Wormsley

There are no affiliations available

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