Discussion Following the Report of Prof. Cohen

  • Wolfram Domschke
  • Hanns Gerd Dammann
  • B. M. Peskar
  • K. H. Holtermüller
Conference paper


Can you justify the statement that damage is not related to cyclooxygenase inhibition, because clinically it looks to me as though it actually fits very well with that hypothesis? And, secondly, I am not aware of any evidence that damage associated with tiaprofenic acid is actually any different from that with indomethacin.


Bile Acid Gastric Mucosa Acetylsalicylic Acid Oral Route Tiaprofenic Acid 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Wolfram Domschke
    • 1
  • Hanns Gerd Dammann
    • 2
  • B. M. Peskar
    • 3
  • K. H. Holtermüller
    • 4
  1. 1.Medizinische Klinik mit PoliklinikUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Krankenhaus BethanienHamburg 20Germany
  3. 3.Arbeitsgruppe Experimentelle Klinische MedizinRuhr-Universität BochumBochum 1Germany
  4. 4.1. Medizinische KlinikSt. Markus-KrankenhausFrankfurt/Main 50Germany

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