Discussion Following the Report of Prof. Miyake

  • Wolfram Domschke
  • Hanns Gerd Dammann
  • B. M. Peskar
  • K. H. Holtermüller
Conference paper


I have a comment which is related to the terminology regarding restitution and the protection of the proliferative zone. The process of restitution can occur, as you have pointed out, within 10–30 min — very rapidly, far more rapidly than cells can actually turn over. These cells do not necessarily come from the proliferative zone. Rapid restitution is not cell proliferation; it is cell migration.


Epithelial Cell Cell Migration Basement Membrane Synthesis Rate Mucosal Damage 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Wolfram Domschke
    • 1
  • Hanns Gerd Dammann
    • 2
  • B. M. Peskar
    • 3
  • K. H. Holtermüller
    • 4
  1. 1.Medizinische Klinik mit PoliklinikUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Krankenhaus BethanienHamburg 20Germany
  3. 3.Arbeitsgruppe Experimentelle Klinische MedizinRuhr-Universität BochumBochum 1Germany
  4. 4.1. Medizinische KlinikSt. Markus-KrankenhausFrankfurt/Main 50Germany

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