Discussion Following the Report of Prof. Granström

  • Wolfram Domschke
  • Hanns Gerd Dammann
  • B. M. Peskar
  • K. H. Holtermüller
Conference paper


A widely used technique used for the measurement of the effects of aspirin and other nonsteroidal anti-inflammatory drugs on thromboxane formation is to administer the drugs and then to take the blood, allow it to clot in vitro, and then measure the TXB2levels in that serum. Do you know whether there is any metabolism of thromboxane in those samples? And whether it is a good measure of TXB2 formation?


Arachidonic Acid Major Metabolite Urinary Metabolite Phospholipid Class Body Production 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Wolfram Domschke
    • 1
  • Hanns Gerd Dammann
    • 2
  • B. M. Peskar
    • 3
  • K. H. Holtermüller
    • 4
  1. 1.Medizinische Klinik mit PoliklinikUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Krankenhaus BethanienHamburg 20Germany
  3. 3.Arbeitsgruppe Experimentelle Klinische MedizinRuhr-Universität BochumBochum 1Germany
  4. 4.1. Medizinische KlinikSt. Markus-KrankenhausFrankfurt/Main 50Germany

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